Hirabara, Shinya Takahashi, Nobunori Fukaya, Naoki Miyake, Hiroyuki Yabe, Yuichiro Kaneko, Atsushi Ito, Takayasu Oguchi, Takeshi Kida, Daihei Hirano, Yuji
...
Published in
Clinical Rheumatology
The aim of this study was to compare the efficacy and retention rates of three biologics (abatacept, tocilizumab, and etanercept) after switching from first-course anti-TNF monoclonal antibody therapy. We performed a retrospective multicenter study of 89 patients who underwent second-course biologic therapy for 52 weeks after switching from first-c...
Cayot, Audrey Laroche, Davy Disson-Dautriche, Anne Arbault, Anaïs Maillefert, Jean-Francis Ornetti, Paul
Published in
Clinical Rheumatology
There are many potential drug interactions that involve the complex cytochromes P450 (CYP) enzyme system when treatments for chronic inflammatory rheumatic diseases are used. This iatrogenic risk is increased in patients taking multiple drugs such as those with rheumatoid arthritis or gout, whatever the type of CYP interaction (substrate, inducer, ...
Fatemi, Alimohammad Moosavi, Mahdi Sayedbonakdar, Zahra Farajzadegan, Ziba Kazemi, Mehdi Smiley, Abbas
Published in
Clinical Rheumatology
We aimed to evaluate the therapeutic effects of atorvastatin on systemic lupus erythematosus disease activity index (SLEDAI). Ninety patients with SLE were consented and randomized to receive either atorvastatin, 20 mg/day, or placebo for 3 months. The primary outcome was change in SLEDAI. Lipids, erythrocyte sedimentation rate (ESR), and C-reactiv...
Espinoza, Luis R. Helliwell, Philip
Published in
Clinical Rheumatology
Mary Sherman was an American orthopedic surgeon who in 1952 published one of the earliest descriptions of psoriatic arthritis in the English literature. In a time when the general consensus by American rheumatologists was that there was no sufficient evidence to consider psoriatic arthritis as a distinct entity, Mary Sherman argued otherwise. Her w...
Breuer, Gabriel S. Ehrenfeld, Michael Rosner, Itzhak Balbir-Gurman, Alexandra Zisman, Devy Oren, Shirley Paran, Daphna
Published in
Clinical Rheumatology
Rituximab is a monoclonal antibody directed against the CD20 antigen on the surface of normal and malignant B lymphocytes. Its use in autoimmune conditions is rapidly expanding. Late-onset neutropenia (LON) is a well-recognized side effect of rituximab therapy in lymphoma patients. Only a small number of cases of LON have been reported in patients ...
Bautista-Molano, Wilson Navarro-Compán, Victoria Landewé, Robert B. M. Boers, Maarten Kirkham, Jamie J. van der Heijde, Désirée
Published in
Clinical Rheumatology
This study aims to investigate how well the Assessment of SpondyloArthritis international Society (ASAS)/Outcome Measures in Rheumatology Clinical Trials (OMERACT) core set and response criteria for ankylosing spondylitis (AS) have been implemented in randomized controlled trials (RCTs) testing pharmacological and non-pharmacological interventions....
Emery, Paul Fleischmann, Roy M. Hsia, Elizabeth C. Xu, Stephen Zhou, Yiying Baker, Daniel
Published in
Clinical Rheumatology
The purpose of this study was to assess the treatment benefit of golimumab + methotrexate (MTX) vs. MTX monotherapy in MTX-naïve patients with severe active rheumatoid arthritis (RA). This was a post hoc analysis of MTX-naïve RA patients in the GO-BEFORE trial who were randomized to receive placebo + MTX (n = 160), golimumab 50 mg + MTX (n = 159), ...
Malas, Fevziye Ünsal Kara, Murat Aktekin, Lale Ersöz, Murat Özçakar, Levent
Published in
Clinical Rheumatology
This study aims to investigate the association between vitamin D levels and distal femoral cartilage thickness in healthy subjects. Eighty patients who were admitted to our outpatient clinic between May and July 2013 were classified into three subgroups according to their 25-OH vitamin D levels of
Kim, Hye Won Park, Jin Kyun Yang, Ji-Ae Yoon, Young Im Lee, Eun Young Song, Yeong Wook Kim, Hang Rae Lee, Eun Bong
Published in
Clinical Rheumatology
Clinical characteristics of antitumor necrosis factor (TNF) agents-related tuberculosis (TB) in ankylosing spondylitis (AS) are not well described. The aim was to compare the incidences and the characteristics of TB in AS and rheumatoid arthritis (RA) during TNF inhibitor treatment. AS (n = 1,322) and RA (n = 3,154) patients who received medical ca...
Gueddari, S. Amine, B. Rostom, S. Badri, D. Mawani, N. Ezzahri, M. Moussa, F. Shyen, S. Abouqal, R. Chkirat, B.
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Published in
Clinical Rheumatology
Juvenile idiopathic arthritis (JIA) is a chronic condition known to cause pain-related complications in youth and affect children’s physical functioning. There is no data in Arabic children with JIA about the impact of illness upon their physical activity. The objective of this study was to explore physical activity (PA) in children and adolescents...
