Marconi, Vincent C Moser, Carlee Gavegnano, Christina Deeks, Steven G Lederman, Michael M Overton, Edgar T Tsibris, Athe Hunt, Peter W Kantor, Amy Sekaly, Rafick-Pierre
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Published in
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Inflammation is associated with end-organ disease and mortality for people with human immunodeficiency virus (PWH). Ruxolitinib, a Jak 1/2 inhibitor, reduces systemic inflammation for individuals without human immunodeficiency virus (HIV) and HIV reservoir markers ex vivo. The goal of this trial was to determine safety and efficacy of ruxolitinib f...
Kumar, Rebecca N Wu, En-Ling Stosor, Valentina Moore, William J Achenbach, Chad Ison, Michael G Angarone, Michael P
Published in
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Coronavirus disease 2019 (COVID-19) has strained healthcare systems with patient hospitalizations and deaths. Anti-spike monoclonal antibodies, including bamlanivimab, have demonstrated reduction in hospitalization rates in clinical trials, yet real-world evidence is lacking. We conducted a retrospective case-control study across a single healthcar...
Hyde, Zoë
Published in
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
The epidemiology of coronavirus disease 2019 in children has been challenging to establish, owing to the high prevalence of asymptomatic infection in this population. Lower secondary attack rates in children compared with adults have been observed in household contact studies, but there is evidence that this may reflect lower testing in children an...
Lipworth, Samuel Vihta, Karina-Doris Chau, Kevin K Kavanagh, James Davies, Timothy George, Sophie Barker, Leanne Vaughan, Ali Andersson, Monique Jeffery, Katie
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Published in
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
The incidence of bloodstream infections (BSIs) caused by Escherichia coli and Klebsiella pneumoniae is increasing, with substantial associated morbidity, mortality, and antimicrobial resistance. Unbiased serotyping studies to guide vaccine target selection are limited. We conducted unselected, population-level genomic surveillance of bloodstream E....
Eyal, Nir Lipsitch, Marc
Published in
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Although vaccines against severe acute respiratory syndrome coronavirus 2 have now been found safe and efficacious, there remains an urgent global health need to test both these vaccines and additional vaccines against the same virus. Under variable conditions, either standard or unusual designs would for both familiar and often-missed reasons make...
Richier, Quentin Plaçais, Léo Lacombe, Karine Hermine, Olivier
Published in
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Van Elslande, Jan Gruwier, Lien Godderis, Lode Vermeersch, Pieter
Published in
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Malgie, Jishnu Schoones, Jan W Pijls, Bart G
Published in
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Yang, Bingyi Wu, Peng Lau, Eric H Y Wong, Jessica Y Ho, Faith Gao, Huizhi Xiao, Jingyi Adam, Dillon C Ng, Tiffany W Y Quan, Jianchao
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Published in
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Disparities were marked in previous pandemics, usually with higher attack rates reported for those in lower socioeconomic positions and for ethnic minorities. We examined characteristics of laboratory-confirmed coronavirus disease 2019 (COVID-19) cases in Hong Kong, assessed associations between incidence and population-level characteristics at the...
Connors, Jean M Iba, Toshiaki Gandhi, Rajesh T
Published in
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
