Wang, Kun Zuo, Peiyuan Liu, Yuwei Zhang, Meng Zhao, Xiaofang Xie, Songpu Zhang, Hao Chen, Xinglin Liu, Chengyun
Published in
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
This study aimed to develop mortality-prediction models for patients with coronavirus disease-2019 (COVID-19). The training cohort included consecutive COVID-19 patients at the First People's Hospital of Jiangxia District in Wuhan, China, from 7 January 2020 to 11 February 2020. We selected baseline data through the stepwise Akaike information crit...
Xiao, Ai Tang Tong, Yi Xin Zhang, Sheng
Published in
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
A novel coronavirus (COVID-19) pandemic threatens the world. Here, we first studied the dynamics profile of SARS-CoV-2 from 56 recovered patients with COVID-19. We found viral shedding occurred up to 6 weeks after onset of symptoms. A prolonged observation period is necessary for older patients. © The Author(s) 2020. Published by Oxford University ...
Jung, Sun-Young Choi, Jae Chol You, Seung-Hun Kim, Won-Young
Published in
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Renin-angiotensin-aldosterone system (RAAS) inhibitors may facilitate host cell entry of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) or attenuate organ injury via RAAS blockade. We aimed to assess the associations between prior use of RAAS inhibitors and clinical outcomes among Korean patients with coronavirus disease 2019 (COVID-1...
Wang, Yubo He, Yong Tong, Jin Qin, Yalan Xie, Ting Li, Jianghua Li, Jianrong Xiang, Jianhua Cui, Yong Higgs, Elizabeth S
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Published in
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
We aimed to further clarify the epidemiological and clinical characteristics of asymptomatic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections. We identified close contacts of confirmed coronavirus disease 2019 (COVID-19) cases in northeast Chongqing, China, who were confirmed by real-time reverse transcription polymerase chai...
Han, Mi Seon Seong, Moon-Woo Heo, Eun Young Park, Ji Hong Kim, Namhee Shin, Sue Cho, Sung Im Park, Sung Sup Choi, Eun Hwa
Published in
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
We report changes in viral load over time in a 27-day-old neonate with coronavirus disease 2019 who presented with fever, cough, and vomiting. Severe acute respiratory syndrome coronavirus 2 RNA was detected in the nasopharynx, oropharynx, stool, saliva, plasma, and urine. The highest viral RNA copies in nasopharynx decreased over time while viral ...
Nosyk, Bohdan Armstrong, Wendy S Del Rio, Carlos
Published in
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) testing and contact tracing have been proposed as critical components of a safe and effective coronavirus disease 2019 (COVID-19) public health strategy. We argue that COVID-19 contact tracing may provide a unique opportunity to also conduct widespread HIV testing, among other health-prom...
Luers, Jan C Rokohl, Alexander C Loreck, Niklas Wawer Matos, Philomena A Augustin, Max Dewald, Felix Klein, Florian Lehmann, Clara Heindl, Ludwig M
Published in
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has spread rapidly worldwide. Given scarce resources, nonlaboratory diagnostics are crucial. In this cross-sectional study, two-thirds of European patients with confirmed COVID-19 reported olfactory and gustatory dysfunction, indicating the ...
Grassin-Delyle, Stanislas Salvator, Hélène Brollo, Marion Catherinot, Emilie Sage, Edouard Couderc, Louis-Jean Naline, Emmanuel Devillier, Philippe
Published in
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
On human lung parenchymal explants, chloroquine concentration clinically achievable in the lung (100 µM) inhibited the lipopolysaccharide-induced release of TNF-ɑ (by 76%), IL-6 (by 68%), CCL2 (by 72%), and CCL3 (by 67%). Besides its antiviral activity, chloroquine might also mitigate the cytokine storm associated with severe pneumonia caused by co...
Marchand-Senécal, Xavier Kozak, Rob Mubareka, Samira Salt, Natasha Gubbay, Jonathan B Eshaghi, Alireza Allen, Vanessa Li, Yan Bastien, Natalie Gilmour, Matthew
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Published in
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
We report diagnosis and management of the first laboratory-confirmed case of coronavirus disease 2019 (COVID-19) hospitalized in Toronto, Canada. No healthcare-associated transmission occurred. In the face of a potential pandemic of COVID-19, we suggest sustainable and scalable control measures developed based on lessons learned from severe acute r...
Maxwell, Daniel N Perl, Trish M Cutrell, James B
Published in
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
