Davis, Chris Tipton, Tom Sabir, Suleman Aitken, Celia Bennett, Susan Becker, Stephan Evans, Tom Fehling, Sarah Katharina Gunson, Rory Hall, Yper
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Published in
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
In October 2015, 65 people came into direct contact with a healthcare worker presenting with a late reactivation of Ebola virus disease (EVD) in the United Kingdom. Vaccination was offered to 45 individuals with an initial assessment of high exposure risk. Approval for rapid expanded access to the recombinant vesicular stomatitis virus-Zaire Ebola ...
Bourke, Claire D Evans, Ceri
Published in
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Wong, Sally Cheuk Ying Tse, Herman Siu, Hon Kei Kwong, Tsz Shan Chu, Man Yee Yau, Felix Yat Sun Cheung, Ingrid Yu Ying Tse, Cindy Wing Sze Poon, Kin Chiu Cheung, Kwok Chi
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Published in
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
The coronavirus disease 2019 (COVID-19) pandemic has put tremendous pressure on the healthcare system worldwide. Diagnostic testing remained one of the limiting factors for early identification and isolation of infected patients. This study aimed to evaluate posterior oropharyngeal saliva (POPS) for severe acute respiratory syndrome coronavirus 2 (...
Dookie, Navisha Padayatchi, Nesri Lessells, Richard J Naicker, Cherise L Chotoo, Sunitha Naidoo, Kogieleum
Published in
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
A case of multidrug-resistant tuberculosis is presented. It highlights the role of whole-genome sequencing, expanded phenotypic drug susceptibility testing, and enhanced case management, offering a more complete understanding of drug susceptibility to Mycobacterium tuberculosis. This approach guides an effective individualized treatment strategy th...
Kou, Samuel C Yang, Shihao Chang, Chia-Jung Ho, Teck-Hua Graver, Lisa
Published in
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
This report presents a novel approach to estimate the total number of COVID-19 cases in the United States, including undocumented infections, by combining the Centers for Disease Control and Prevention's influenza-like illness surveillance data with aggregated prescription data. We estimated that the cumulative number of COVID-19 cases in the Unite...
Faust, Jeremy Samuel
Published in
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Ippolito, Matthew M Flexner, Charles
Published in
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Martin-Blondel, Guillaume Ruiz, Stéphanie Murris, Marlène Faguer, Stanilas Duhalde, Véronigue Eyvrard, Frédéric Izopet, Jacques Mansuy, Jean-Michel Rolland, Yves Delavigne, Karen
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Published in
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Different dosage regimens of hydroxychloroquine are used to manage coronavirus disease 2019 (COVID-19) patients, without information on the pharmacokinetics in this population. Blood samples (n = 101) were collected from 57 COVID-19 patients for 7 days, and concentrations were compared with simulated kinetic profiles. Hydroxychloroquine exposure is...
Taylor, Stephanie Parks Kowalkowski, Marc A Beidas, Rinad S
Published in
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
The coronavirus disease 2019 pandemic represents a global crisis that has received extraordinary response from healthcare workers and scientists. One critical but potentially overlooked field in a pandemic is implementation science-the study of methods to reduce the research-to-practice gap. In this Viewpoint, we discuss the important role of imple...
D'Souza, Alaric W Moodley-Govender, Eshia Berla, Bertram Kelkar, Tejas Wang, Bin Sun, Xiaoqing Daniels, Brodie Coutsoudis, Anna Trehan, Indi Dantas, Gautam
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Published in
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Prophylactic cotrimoxazole treatment is recommended in human immunodeficiency virus (HIV)-exposed, uninfected (HEU) infants, but the effects of this treatment on developing HEU infant gut microbiotas and resistomes are largely undefined. We analyzed whole-metagenome sequencing data from 163 longitudinally collected stool samples from 63 HEU infants...
