Vera, Michael A Koch, Christopher D Kavsak, Peter A El-Khoury, Joe M
Published in
Clinica chimica acta; international journal of clinical chemistry
Heart-type fatty acid binding protein (H-FABP), a low molecular weight protein found primarily in myocardial tissue, has been identified as a potential biomarker in the detection of acute coronary syndrome and acute kidney injury. To further investigate clinical utility, we sought to establish an upper reference limit (URL) of H-FABP within a healt...
Zhang, Jingya Wei, Qian Dong, Dong Ren, Li
Published in
Clinica chimica acta; international journal of clinical chemistry
To explore the application value of breast cancer tumor markers tissue polypeptide specific antigen (TPS), carbohydrate antigen 15-3 (CA15-3), carcinoembryonic antigen (CEA), carbohydrate antigen 125 (CA125) detection alone or in combination for the monitoring of distant metastasis of breast cancer. The clinical data of 389 female breast cancer pat...
Zhao, Xiao-Ying Qiao, Guang-Ming Liu, Fang
Published in
Clinica chimica acta; international journal of clinical chemistry
Mucopolysaccharidosis type II (MPS II) or Hunter syndrome is a rare X-linked recessive genetic disease resulting from deficient activity of the iduronate-2-sulfatase(IDS) enzyme and the accumulation of glycosaminoglycans in almost all cells, tissues and organs, which makes viscera function impaired.This study retrospectively analyzed the clinical c...
Teng, Hua Liang, Chen Liang, Desheng Li, Zhuo Wu, Lingqian
Published in
Clinica chimica acta; international journal of clinical chemistry
Galloway-Mowat syndrome (GAMOS) is an extremely rare clinically heterogeneous autosomal or X-linked inherited recessive disease characterized by early-onset steroid-resistant nephrotic syndrome (SRNS), microcephaly and neurological impairment. In this study, two siblings mainly presenting with decreased head circumference, hypotonia, gross motor de...
Liu, Yiwen Wen, Jianping Huang, Weiguo
Published in
Clinica chimica acta; international journal of clinical chemistry
Nasopharyngeal carcinoma (NPC) is a malignant epithelial tumor with a unique geographical distribution, primarily prevalent in East Africa and Asia. Although there is an increased understanding of the pathogenesis and risk factors of NPC, prevention and treatment efforts remain limited. Various studies have indicated that exosomes are actively invo...
Madatali Abuwani, Asmita Priyadarshini Dash, Shweta Ganesan, Raja Renu, Kaviyarasi Vellingiri, Balachandar Kandasamy, Sabariswaran C R, Sundara Rajan Valsala Gopalakrishnan, Abilash
Published in
Clinica chimica acta; international journal of clinical chemistry
Fatty liver disease (FLD) is one of the largest burdens to human health worldwide and is associated with gut microbiome and metabolite stability. Engineered liver tissues have shown promise in restoring liver functions in non-alcoholic FLD (NAFLD), hepatitis and cirrhosis. Fatty liver, largely noted in obesity and hepatic cancer, is highly fatal an...
Loh, Tze Ping Smith, Alison F Bell, Katy J L Lord, Sarah J Ceriotti, Ferruccio Jones, Graham Bossuyt, Patrick Sandberg, Sverre Horvath, Andrea Rita
Published in
Clinica chimica acta; international journal of clinical chemistry
Analytical performance specifications (APS) for measurands describe the minimum analytical quality requirements for their measurement. These APS are used to monitor and contain the systematic (trueness/bias) and random errors (precision/imprecision) of a laboratory measurement to ensure the results are "fit for purpose" in informing clinical decisi...
Luo, Qing Wen, Xia Zhou, Jiahong Chen, Yang Lv, Zhiyu Shen, Xing Liu, Jinbo
Published in
Clinica chimica acta; international journal of clinical chemistry
The mitochondrial tRNA translation optimization 1 (MTO1) gene, which is closely related to defective mitochondrial oxidative phosphorylation, is an evolutionarily conserved protein expressed in high energy-demanding tissues and is associated with complex oxidative phosphorylation deficiency type 10 (COXPD10) in humans. Related cases and studies are...
Peng, Ziyi Hu, Qiuzhi Fang, Shuai Zhang, Xun Hong, Xin Tao, Lili Pan, Jinchang Jiang, Meina Bai, Huihui Wu, Yinuo
...
Published in
Clinica chimica acta; international journal of clinical chemistry
Circular RNAs (CircRNAs) have been found to possess vital functions in tumorigenesis of various cancer types, including non-small cell lung cancer (NSCLC). The aim of this study was to identify and explore the diagnostic values of the newly found Toll interacting protein (TOLLIP)-derived circRNA (circTOLLIP) for liquid biopsy in NSCLC. RNase R and ...
Basthi Mohan, Pooja Nagaraju, Shankar Prasad Rangaswamy, Dharshan Musunuri, Balaji Prabhu Attur, Ravindra Bhat, Ganesh Shailesh, Shetty, Shiran
Published in
Clinica chimica acta; international journal of clinical chemistry
Acute kidney injury (AKI) in liver cirrhosis is associated with poor clinical outcomes including an increased long and short-term mortality. The common type of AKI observed in patients with cirrhosis are prerenal AKI (PRA), hepatorenal syndrome (HRS) and acute tubular necrosis (ATN). Despite the growing knowledge and uniform definition for the diag...
