Fang, Yingye Chen, Ling Imoukhuede, P. I.
Published in
Cellular and Molecular Bioengineering
Introduction Abnormal angiogenesis is central to vascular disease and cancer, and noninvasive biomarkers of vascular origin are needed to evaluate patients and therapies. Vascular endothelial growth factor receptors (VEGFRs) are often dysregulated in these diseases, making them promising biomarkers, but the need for an invasive biopsy has limited b...
Kohs, Tia C. L. Clarin, Samuel N. Carter, Rich G. Mundorff, Karl Imoukhuede, Princess I. Ramamurthi, Anand Bao, Gang King, Michael R. McCarty, Owen J. T.
Published in
Cellular and Molecular Bioengineering
Kohs, Tia C. L. Clarin, Samuel N. Carter, Rich G. Mundorff, Karl Imoukhuede, Princess I. Ramamurthi, Anand Bao, Gang King, Michael R. McCarty, Owen J. T.
Published in
Cellular and Molecular Bioengineering
Promotion and tenure (P&T) remain the central tenets of academia. The criteria for P&T both create and reflect the mission of an institution. The discipline of biomedical engineering is built upon the invention and translation of tools to address unmet clinical needs. ‘Broadening the bar’ for P&T to include efforts in innovation, entrepreneurship, ...
Chen, Xiaoxiao Xia, Youjun Du, Wenqiang Liu, Han Hou, Ran Song, Yiyu Xu, Wenhu Mao, Yuxin Chen, Jianfeng
Published in
Cellular and Molecular Bioengineering
Introduction Cancer metastasis is associated with increased cancer incidence, recurrence, and mortality. The role of cell contact guidance behaviors in cancer metastasis has been recognized but has not been elucidated yet. Methods The contact guidance behavior of cancer cells in response to topographical constraints is identified using microgrooved...
King, Michael R.
Published in
Cellular and Molecular Bioengineering
López-Rodulfo, Iván M. Villa-Martínez, Elisa Rios, Amelia Escalante, Bruno
Published in
Cellular and Molecular Bioengineering
Introduction The nitric oxide synthase (eNOS) is an important regulator of vascular homeostasis. eNOS is modulated by intracellular mechanisms that include protein–protein interaction with Caveolin-1 (Cav). Cav binds to and impairs eNOS activation reducing vascular permeability and angiogenesis. Blocking of eNOS by Cav has been proposed as therapeu...
Weber, Callie M Harris, Mikayla N Zic, Sophia M Sangha, Gurneet S Arnold, Nicole S Dluzen, Douglas F Clyne, Alisa Morss
Published in
Cellular and molecular bioengineering
Women are at elevated risk for certain cardiovascular diseases, including pulmonary arterial hypertension, Alzheimer's disease, and vascular complications of diabetes. Angiotensin II (AngII), a circulating stress hormone, is elevated in cardiovascular disease; however, our knowledge of sex differences in the vascular effects of AngII are limited. W...
Sasson, Daniel C. Islam, Sara Duan, Kaiti Dash, Biraja C. Hsia, Henry C.
Published in
Cellular and Molecular Bioengineering
Introduction hiPSC-VSMCs have been suggested as therapeutic agents for wound healing and revascularization through the secretion of proangiogenic factors. However, methods of increasing cell paracrine secretion and survivability have thus far yielded inconsistent results. This study investigates the effect of pre-conditioning of hiPSC-VSMCs with TN...
King, Michael R.
Published in
Cellular and Molecular Bioengineering
There is a growing recognition that scientific articles featuring women and people of color as first and last (senior) author are undercited in the literature relative to male and non-minority race authors. Some limited tools now exist to analyze the diversity of manuscript bibliographies, with acknowledged limitations. Recently the journal editors...
Kleebayoon, Amnuay Wiwanitkit, Viroj
Published in
Cellular and molecular bioengineering
