Hou, Panpan Yang, Kongxiang Jia, Penghui Liu, Lan Lin, Yuxin Li, Zibo Li, Jun Chen, Shuliang Guo, Shuting Pan, Ji'An
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Published in
Cell research
Autophagy is a conserved process that delivers cytosolic substances to the lysosome for degradation, but its direct role in the regulation of antiviral innate immunity remains poorly understood. Here, through high-throughput screening, we discovered that CCDC50 functions as a previously unknown autophagy receptor that negatively regulates the type ...
Liu, Xiaoling Lai, Weiyi Li, Yao Chen, Shaokun Liu, Baodong Zhang, Ning Mo, Jiezhen Lyu, Cong Zheng, Jing Du, Ya-Rui
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Published in
Cell research
Liu, Jing Peng, Yunhua Shi, Le Wan, Lixin Inuzuka, Hiroyuki Long, Jiangang Guo, Jianping Zhang, Jinfang Yuan, Min Zhang, Shuangxi
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Published in
Cell Research
Whether glucose is predominantly metabolized via oxidative phosphorylation or glycolysis differs between quiescent versus proliferating cells, including tumor cells. However, how glucose metabolism is coordinated with cell cycle in mammalian cells remains elusive. Here, we report that mammalian cells predominantly utilize the tricarboxylic acid (TC...
Zhang, Kaiming Pintilie, Grigore D Li, Shanshan Schmid, Michael F Chiu, Wah
Published in
Cell research
Vagnozzi, Ronald J Molkentin, Jeffery D
Published in
Cell research
Berger, Imre Schaffitzel, Christiane
Published in
Cell research
Chi, Ximin Li, Xiaorong Chen, Yun Zhang, Yuanyuan Su, Qiang Zhou, Qiang
Published in
Cell research
Huang, Furong Chen, Hongyan Zhu, Xiaolin Gong, Tongyang Li, Xukun Hankey, William Wang, Hongyan Chen, Zhong Wang, Qianben Liu, Zhihua
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Published in
Cell research
Blériot, Camille Liu, Zhaoyuan Ginhoux, Florent
Published in
Cell research
Bai, Guanhua Wang, Yu Zhang, Mingjie
Published in
Cell research
Inhibitory synapses are also known as symmetric synapses due to their lack of prominent postsynaptic densities (PSDs) under a conventional electron microscope (EM). Recent cryo-EM tomography studies indicated that inhibitory synapses also contain PSDs, albeit with a rather thin sheet-like structure. It is not known how such inhibitory PSD (iPSD) sh...