OMICS, a multidisciplinary friendship.
Published in Cell death & disease
JNK modulates FOXO3a for the expression of the mitochondrial death and mitophagy marker BNIP3 in pathological hypertroph...
Published in Cell death & disease
Bcl-2 E1B 19-KDa interacting protein 3 (BNIP3) is a mitochondrial death and mitophagy marker, which is involved in inducing cardiac remodeling post myocardial infarction. In this study, we show that BNIP3 expression increases in stressed cardiomyocytes in vitro and in response to pressure overload in vivo, and that its transcription is directly rel...
Short interfering RNA against STAT1 attenuates cisplatin-induced ototoxicity in the rat by suppressing inflammation.
Published in Cell death & disease
Cisplatin is widely used for treating various solid tumors. However, this drug produces dose-limiting ototoxicity and nephrotoxicity, which significantly reduce the quality of life of cancer patients. While nephrotoxicity could be alleviated by diuresis, there is currently no approved treatment for hearing loss. Previous studies show that the ROS a...
Primary hematopoietic cells from DBA patients with mutations in RPL11 and RPS19 genes exhibit distinct erythroid phenoty...
...Published in Cell Death and Disease
Metformin inhibits melanoma development through autophagy and apoptosis mechanisms.
...Published in Cell Death and Disease
Zinc chelation: a metallothionein 2A's mechanism of action involved in osteosarcoma cell death and chemotherapy resistan...
Published in Cell Death and Disease
Plasminogen activator urokinase expression reveals TRAIL responsiveness and supports fractional survival of cancer cells...
Published in Cell Death and Disease
Glucose metabolism and hexosamine pathway regulate oncogene-induced senescence.
Published in Cell Death and Disease
Lysyl oxidase activity regulates oncogenic stress response and tumorigenesis.
...Published in Cell Death and Disease
