Luo, Yi Waladali, Wafi Li, Shiwen Zheng, Xinmin Hu, Liquan Zheng, Hang Hu, Wanli Chen, Chan
Published in
Cell biology international
Abundant evidence indicates that estrogens have an important role in the pathology of benign prostatic hyperplasia (BPH). To investigate the effect of 17beta-estradiol (E2) on the proliferation and apoptosis of prostatic smooth muscle cells (PSMCs), rat PSMCs were obtained and exposed to gradient concentrations (0.1-100 nmol/l) of E2 over varying a...
Kawai, Yoshiki Wada, Fumitaka Sugimura, Yoshiaki Maki, Masatoshi Hitomi, Kiyotaka
Published in
Cell biology international
Transglutaminase is a Ca2+-dependent enzyme catalyzing protein cross-linking reactions. We investigated the contribution of this enzyme to the resealing of the injured plasma membrane in animal cells, using a lung cancer-derived cell line, A549. After mechanical injury by razor-scratching, the level of membrane resealing was estimated by differenti...
Murakami, Masaru Kondo, Shoko Funaba, Masayuki
Published in
Cell biology international
Mouse TGF-beta type I receptor, Alk5, encodes two types of mRNA generated by alternative splicing of four amino acids in the extracellular region. In the present study, the expression and function of alternative splice variants of Alk5, i.e., Alk5-L (Alk5 with the four amino acids) and Alk5-S (Alk5 without the four amino acids), were examined. Expr...
Hashizume, Toshihiro Fukuda, Takayuki Nagaoka, Tadahiro Tada, Hiroko Yamada, Hidenori Watanabe, Kazuhide Salomon, David S Seno, Masaharu
Published in
Cell biology international
ErbB2, which is a member of the epidermal growth factor (erbB) receptor family, is frequently overexpressed in breast and ovarian cancers. Antibody and small molecule anti-tyrosine kinase inhibitors have been developed for targeted therapies for cancers overexpressing erbB2. Internalization and downregulation of erbB2, which is induced by a ligand,...
He, Huixia Yu, Jinhua Liu, Yuan Lu, Shouchang Liu, Hongchen Shi, Junnan Jin, Yan
Published in
Cell biology international
Two crucial growth factors, FGF2 and TGFbeta1, were investigated in this study to determine their inductive effects on the odontoblastic differentiation of human dental pulp stem cells (DPSCs) in vitro. DPSCs were isolated by immunomagnetic bead selection using the STRO-1 antibody, and then co-cultured respectively with FGF2, TGFbeta1 and FGF2+TGFb...
Muhammad Irfan-maqsood
Published in
Cell Biology International
Muhammad Irfan-maqsood
Published in
Cell Biology International
