Pimenta, Jefferson Rios Ueda, Serli Kiyomi Nakao Peixoto, Renata D’Alpino
Published in
Case Reports in Oncology
Metastatic pancreatic ductal adenocarcinoma (PDAC) has a dismal prognosis. Until recently, cytotoxic chemotherapy was the only treatment option. Currently, there are subgroups of patients with PDAC either with somatic or germline mutations who are candidates for targeted agents. Germline mutations in the BRCA1 and BRCA2 genes promote the incapacity...
Liu, I-Chia Giap, Fantine Mailhot-Vega, Raymond B. Bradley, Julie A. Mendenhall, Nancy P. Okunieff, Paul Lu, Li Jantz, Michael A. Daily, Karen Spiguel, Lisa
...
Published in
Case Reports in Oncology
Purpose: Radiation recall dermatitis (RRD) is a rare complication that occurs after completion of radiation therapy (RT) and initiation of a precipitating agent, most commonly chemotherapeutic medications. Various theories attempt to explain the mechanism, including activation of the body’s inflammatory pathways through nonimmune activation. Likewi...
Chia, Brendan Seng Hup Nei, Wen Long Charumathi, Sabanayagam Fong, Kam Weng Tan, Min-Han
Published in
Case Reports in Oncology
The use of circulating cell-free tumour DNA (ctDNA) is established in metastatic lung adenocarcinoma to detect and monitor sensitising EGFR mutations. In early-stage disease, there is very little data supporting its role as a potential biomarker. We report on a prospective cohort of 9 limited-stage EGFR mutant lung cancer patients who were treated ...
Acosta Rojas, Angel Collazo-Lorduy, Ana Remon, Jordi Hernando Requejo, Ovidio Jiménez-Munarriz, Beatriz Rubio Rodríguez, María Carmen De Castro, Javier
Published in
Case Reports in Oncology
The incidence of lung cancer during pregnancy is rising due to the high rate of smokers in young women and the late mean age of pregnancy; in addition, considering that the patients are young women with a higher incidence of molecular alterations, molecular testing in lung adenocarcinoma should always be performed, even in pregnancy. Here, we repor...
Mohamed, Sabah E. Yassin, Mohamed A.
Published in
Case Reports in Oncology
Off-label drug use refers to drug use beyond the specifications authorized for marketing [J Med Case Rep. 2014 Dec;8(1):303]. Eltrombopag is a thrombopoietin receptor agonist that has been used in treating thrombocytopenia due to chronic liver disease (CLD) as an off-label medication. Treatment of thrombocytopenia in patients with CLD constitute a ...
Abu-Tineh, Mohammad Elmalik, Hind Yassin, Mohamed A.
Published in
Case Reports in Oncology
Metastatic ovarian cancer to the breast is a rare presentation, with limited cases reported worldwide. Common sites for distant metastasis in ovarian cancer are to the liver, lung, and pleura [Dauplat et al. Cancer. 1987 Oct 1;60(7):1561–6]. Usually, such cases predict poor prognosis with troublesome management. We present one challenging case of a...
Ashjaei, Bahar Ghamari Khameneh, Afshar Darban Hosseini Amirkhiz, Gisoo
Published in
Case Reports in Oncology
Castleman disease is a rare cause of retroperitoneal mass in children. Clinical presentation and laboratory findings are usually nonspecific. Imaging shows features of a hypervascular or soft tissue mass. We present a 12-year-old boy who complained of frequent colds, fatigue, and failure to gain weight for the past 4 years who was referred to our h...
Yadav, Dhiraj Kumar Paul, Thushara Alhamar, Mohamed Inamdar, Kedar Guo, Yue
Published in
Case Reports in Oncology
We present a very rare case of pure erythroid leukemia arising in a young patient with sickle cell disease being treated with hydroxyurea for almost 5 years. Diagnosing and managing this rare condition has been a challenge and the majority of patients with pure erythroid leukemia have a very poor prognosis with survival in months despite treatment....
Houessinon, Aline Moreira, Aurélie Bettoni, Jérèmie Schoonaker, Marine Sauzay, Chloé Galmiche, Antoine Coutte, Alexandre Biet, Aurélie Krzisch, Claude Chauffert, Bruno
...
Published in
Case Reports in Oncology
The survival of patients with head and neck squamous cancer with locoregional recurrence is short if salvage surgery or radiation cannot be performed. Systemic chemotherapy based on platinum salts and cetuximab produces only partial and transient responses. Immune checkpoint inhibitors (i.e., nivolumab) lead to a low complete response rate of only ...
Imataki, Osamu Uemura, Makiko
Published in
Case Reports in Oncology
An 80-year-old Japanese male was treated with chemotherapy consisting of cyclophosphamide, doxorubicin, vincristine, and prednisolone, for non-Hodgkin lymphoma. Nine months after the chemotherapy, he was diagnosed with acute myeloid leukemia (AML) (M4) with translocation 8p11 and 22q13. The patient bone marrow indicated a remarkable degree of sea-b...
