ASPO Distinguished Achievement Award Lecture. Epidemiological studies using biological markers: issues for epidemiologis...
New opportunities for interdisciplinary cancer communication.
Ethnicity and cancer risk in São Paulo, Brazil.
Data from the São Paulo Cancer Registry (Brazil) for the period 1969-1974 are used to investigate ethnic differentials in cancer risk. Risks for specific cancers were estimated for mulattos and blacks relative to whites, using a case-control approach with other cancers as controls. For both sexes, blacks and mulattos are at higher risk than whites ...
The new era of cancer epidemiology.
Lung cancer in nonsmoking women: a multicenter case-control study.
...The association between exposure to environmental tobacco smoke and lung cancer in female lifetime nonsmokers was evaluated using data collected during the first 3 years of an ongoing case-control study. This large, multicenter, population-based study was designed to minimize some of the methodological problems which have been of concern in previou...
Testing for germ line p53 mutations in cancer families.
Changing patterns of lung cancer incidence by histological type.
Using data from five registries covering 7% of the U.S. population, we investigated lung carcinoma incidence trends from 1969-86 by histological type, sex, race, age, calendar time period, and cohort year of birth. Among white men, squamous cell carcinoma was the most frequent histological type, but by the mid-1980s the age-adjusted rates were decr...
Classification of aberrant crypt foci and microadenomas in human colon.
Aberrant crypt foci (ACF) can be observed and quantified on the mucosal surface of formalin-fixed human colon resections after staining with methylene blue. To determine whether these ACF could be identified in fresh tissue, 10 colon resections were collected after surgery for colorectal cancer. Unfixed and fixed flat normal colonic mucosa from eac...
A smoking cessation intervention for head and neck cancer patients: trial design, patient accrual, and characteristics.
This paper describes the aims, study design, and patient accrual and characteristics from an ongoing randomized controlled trial evaluating a surgeon- and dentist-delivered smoking cessation intervention for head and neck cancer patients. Subjects (n = 186) accrued into the trial are profiled in terms of demographics, medical and treatment descript...
Plasma pepsinogens, nutrients, and diet in areas of Italy at varying gastric cancer risk.
...In a survey of 930 adults aged 35-74 years randomly sampled from the general population of four areas of Italy at different risks for gastric cancer (GC), plasma levels of pepsinogens (PGI and PGII) and fat-soluble vitamins were assayed. Pepsinogen levels were used to identify individuals with chronic atrophic gastritis (CAG). Severe CAG (PGI 20 p...
