Modulation of Chemotherapy-Induced Mucositis.
Published in Cancer control : journal of the Moffitt Cancer Center
The Role of Lymphoscintigraphy in Staging.
Published in Cancer control : journal of the Moffitt Cancer Center
Melanoma Metastasis.
Published in Cancer control : journal of the Moffitt Cancer Center
Cancer metastasis requires a series of sequential steps, each of which is rate limiting. Neoplasms are biologically heterogeneous, and the process of metastasis is highly selective. Multiple metastases often differ in biologic characteristics and can change during the course of the disease. Clonal analysis of human melanoma suggest that systemic, p...
Genetics of Cutaneous Malignant Melanoma.
Published in Cancer control : journal of the Moffitt Cancer Center
An increase in the clinical significance of cutaneous malignant melanoma has paralleled a dramatic increase in the rate of death from this disease. The critical genetic changes associated with the genesis and progression of this disease are only beginning to be identified. This review highlights genetic changes in cutaneous melanoma and discusses t...
Immunotherapy of Human Melanoma With Gene-Modified Tumor Cell Vaccines.
Published in Cancer control : journal of the Moffitt Cancer Center
The incidence of melanoma in the United States is increasing at a faster rate than that of any other cancer. The prognosis for metastatic disease is poor, and more effective treatments for disseminated disease are needed. Since melanoma is one of the more immunogenic tumors, strategies have focussed on immune recognition. In vitro studies suggest t...
Management of Extremity Lymphedema.
Published in Cancer control : journal of the Moffitt Cancer Center
Chronic lymphedema is almost always a permanent and often progressive condition. In most cases, neither medical nor surgical means can completely relieve the effects of lymphedema. Surgical management of chronic lymphedema has high morbidity and a success rate of only 30%, and many patients return to their presurgical limb girth within three to fou...
Accurate Nodal Staging of Malignant Melanoma.
...Published in Cancer control : journal of the Moffitt Cancer Center
The incidence of malignant melanoma is increasing at a faster pace than that of any other cancer in the United States. It is estimated that people born in the year 2000 will have a 1:75 risk of developing melanoma sometime during his or her lifetime. Stimulated by novel lymphatic mapping techniques, the surgical care of the melanoma patient is evol...
Progress in the Prevention and Management of Malignant Melanoma.
Published in Cancer control : journal of the Moffitt Cancer Center
The Role of Research in Cost Containment.
Published in Cancer control : journal of the Moffitt Cancer Center
Melanoma and Skin Cancer Control: An International Perspective.
Published in Cancer control : journal of the Moffitt Cancer Center
Approximately one million Americans are diagnosed with skin cancer each year. Since melanoma and skin cancer are amenable to prevention, education, and early detection, efforts to reduce the incidence of and death from melanoma have developed in many countries. Programs promoting behavioral changes and the incorporation of skin cancer control into ...
