Zhang, Qiuqiu Zhang, Qianwei Li, Huiyuan Zhao, Xiaofei Zhang, Han
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Cancer Cell International
BackgroundChoroidal melanoma is the most common primary intraocular malignancy that occurs in adults. Lithium Chloride Promotes Apoptosis in Human Leukemia NB4 Cells by Inhibiting Glycogen Synthase Kinase-3 Beta. In this study, we aimed to understand whether LiCl exerts anticancer effects on choroidal melanoma cells and elucidate the underlying mol...
Luo, Yin Liu, Yitong Wang, Chengkun Gan, Runliang
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Cancer Cell International
Epstein-Barr virus (EBV) is closely associated with multiple human cancers. EBV-associated cancers are mainly lymphomas derived from B cells and T cells (Hodgkin lymphoma, Burkitt lymphoma, NK/T-cell lymphoma, and posttransplant lymphoproliferative disorder (PTLD)) and carcinomas derived from epithelial cells (nasopharyngeal carcinoma and gastric c...
Yu, Zhao-liang Chen, Yu-feng Zheng, Bin Cai, Ze-rong Zou, Yi-feng Ke, Jia Lan, Ping Gao, Feng Xiao-jian,
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Cancer Cell International
BackgroundCancer stem cells (CSCs) are a small subpopulation of cells within tumors with stem cell property. Increased evidence suggest that CSCs could be responsible for chemoresistance and recurrence in colorectal cancer (CRC). However, a reliable therapeutic target on CSCs is still lacking.MethodsHere we describe a two-step strategy to generate ...
Yang, Jiarui Liang, Hao Hu, Kunpeng Xiong, Zhiyong Cao, Mingbo Zhong, Zhaozhong Yao, Zhicheng Deng, Meihai
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Cancer Cell International
BackgroundFor patients with hepatocellular carcinoma (HCC) with microvascular invasion (MVI) after curative resection, the effects of various postoperative adjuvant therapies are not summarized in detail, and the comparison between the effects of various adjuvant therapies is still unclear. Thus, we collected existing studies on postoperative adjuv...
Chen, Yan Li, Jun Xiao, Jia-Kun Xiao, Lei Xu, Bin-Wu Li, Chen
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Cancer Cell International
BackgroundOsteosarcoma is one of the most prevalent primary bone tumours in adolescents. Accumulating evidence shows that aberrant expression of the long non-coding RNA (lncRNA) NEAT1 and microRNA-483 (miR-483) contribute to the epithelial-mesenchymal transition (EMT), invasion and metastasis of tumour cells. However, the potential regulatory effec...
Lei, Jie Chen, Peng Zhang, Feng Zhang, Na Zhu, Jianfei Wang, Xiaoping Jiang, Tao
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Cancer Cell International
BackgroundExosomes are known to transmit microRNAs (miRNAs) to affect cancer progression, while the role of M2 macrophages-derived exosomes (M2 exosomes) conveying miR-501-3p in lung cancer (LC) remains unknown. We aim to explore the role of exosomal miR-501-3p in LC development via targeting WD repeat domain 82 (WDR82).MethodsLung cancer tissue an...
Simpson, K. Conquer-van Heumen, G. Watson, K. L. Roth, M. Martin, C. J. Moorehead, R. A.
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Cancer Cell International
BackgroundMicroRNAs are a class of non-coding RNAs that regulate gene expression through binding to mRNAs and preventing their translation. One family of microRNAs known as the miR-200 family is an important regulator of epithelial identity. The miR-200 family consists of five members expressed in two distinct clusters; the miR-200c/141 cluster and...
Zhou, Sitong Ouyang, Wen Zhang, Xi Liao, Lexi Pi, Xiaobing Yang, Ronghua Mei, Baiqiang Xu, Huaiyuan Xiang, Shijian Li, Jiehua
...
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Cancer Cell International
Background Utrophin ( UTRN ), as a tumor suppressor gene, is involved in various cancer progression. The function of UTRN in the melanoma process and the related molecular mechanisms are still unclear. Herein, we studied the function of UTRN in melanoma growth and the relevant molecular mechanisms. Methods Using the GEO database and UCSC Xena proje...
Wang, Yu
Published in
Cancer Cell International
BackgroundLung adenocarcinoma (LUAD) is the most common histological subtype of lung cancer, with a poor prognosis. The roles of circular RNAs (circRNAs) in tumors have been initially clarified. In this study, we probed into the functions and underlying molecular mechanisms of circ-ANXA7 in LUAD.MethodsAccording to circRNA microarray analysis based...
Wang, Lianghai Zhou, Lisha Hou, Jun Meng, Jin Lin, Ke Wu, Xiangwei Chen, Xueling
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Cancer Cell International
An amendment to this paper has been published and can be accessed via the original article.