Bernd, Lamprecht Joan, B Soriano Michael, Studnicka Bernhard, Kaiser Lowie, E Vanfleteren Louisa, Gnatiuc Peter, Burney Marc, Miravitlles Francisco, García-Rio Kaveh, Akbari
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Published in
CHEST Journal
Even with substantial heterogeneity in COPD prevalence, COPD underdiagnosis is universally high. Because effective management strategies are available for COPD, spirometry can help in the diagnosis of COPD at a stage when treatment will lead to better outcomes and improved quality of life.
Fysh, Edward T H Tremblay, Alain Feller-Kopman, David Mishra, Eleanor K Slade, Mark Garske, Luke Clive, Amelia O Lamb, Carla Boshuizen, Rogier Ng, Benjamin J
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Published in
Chest
The incidence of IPC-related pleural infection was low. The overall mortality risk from pleural infection in patients treated with IPC was only 0.29%. Antibiotics should cover S aureus and gram-negative organisms until microbiology is confirmed. Postinfection pleurodesis is common and often allows removal of IPC. Heterogeneity in management is comm...
Woodcock, Ashley Bleecker, Eugene R Lötvall, Jan O'Byrne, Paul M Bateman, Eric D Medley, Hilary Ellsworth, Anna Jacques, Loretta Busse, William W
Published in
Chest
The efficacy of once-daily FF/VI was similar to bid FP/SAL in improving lung function in patients with persistent asthma. No safety issues were identified.
Kohler, Malcolm Craig, Sonya Pepperell, Justin C T Nicoll, Debby Bratton, Daniel J Nunn, Andrew J Leeson, Paul Stradling, John R
Published in
Chest
ISRCTN Register; No.: ISRCTN 34164388; URL: http://isrctn.org.
García, Xaime Simon, Peter Guyette, Francis X Ramani, Ravi Alvarez, Rene Quintero, Jorge Pinsky, Michael R
Published in
Chest
Baseline TFC can discriminate patients with ADHF from non-ADHF dyspnea in the ED.
Woodman, Lucy Bianca Wan, Wing Yan Heidi Milone, Roberta Grace, Ken Sousa, Ana Williamson, Rick Brightling, Christopher Edward
Published in
Chest
The airway epithelium plays a central role in wound repair and host defense and is implicated in the immunopathogenesis of asthma. Whether there are intrinsic differences between the synthetic capacity of epithelial cells derived from subjects with asthma and healthy control subjects and how this mediator release is modulated by antiinflammatory th...
Fazio, Nicola Granberg, Dan Grossman, Ashley Saletan, Stephen Klimovsky, Judith Panneerselvam, Ashok Wolin, Edward M
Published in
Chest
ClinicalTrials.gov; No.: NCT00412061
Helm, Emma J Rahman, Najib M Talakoub, Omid Fox, Danial L Gleeson, Fergus V
Published in
Chest
It is conventionally taught that the intercostal artery is shielded in the intercostal groove of the superior rib. The continuous course and variability of the intercostal artery, and factors that may influence them, have not been described in a large number of arteries in vivo. Maximal intensity projection reformats in the coronal plane were produ...
Bailey, Damian M Rimoldi, Stefano F Rexhaj, Emrush Pratali, Lorenza Salinas Salmòn, Carlos Villena, Mercedes McEneny, Jane Young, Ian S Nicod, Pascal Allemann, Yves
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Published in
Chest
Healthy highlanders display a moderate, sustained elevation in oxidative-nitrosative stress that, unlike the equivalent increase evoked by acute hypoxia in healthy lowlanders, failed to affect vascular function. Its more marked elevation in patients with CMS may contribute to systemic vascular dysfunction.
Lee, Kai K Savani, Alka Matos, Sergio Evans, David H Pavord, Ian D Birring, Surinder S
Published in
Chest
Four-hour cough frequency correlates highly with 24-h cough frequency recordings and relates equally well with subjective measures in chronic cough. Short-duration cough monitoring could be a practical tool to validate the presence of cough and assess response to trials of therapy in the clinic setting.