We should assess early for extubation - In response to: "Intubation in burns patients-Are we following the guidance? A 5...
Published in Burns : journal of the International Society for Burn Injuries
Published in Burns : journal of the International Society for Burn Injuries
Published in Burns : journal of the International Society for Burn Injuries
We aimed to determine the incidence of childhood burn injuries in rural Ghana and describe modifiable household risk factors to inform prevention initiatives. We performed a cluster-randomized, population-based survey of caregivers of children in a rural district in Ghana, representing 2713 households and 14,032 children. Caregivers were interviewe...
Published in Burns : journal of the International Society for Burn Injuries
A need exists to improve the efficiency of clinical trials in burn care. The objective of this study was to validate "Persistent Organ Dysfunction" plus death as endpoint in burn patients and to demonstrate its statistical efficiency. This secondary outcome analysis of a dataset from a prospective international multicenter RCT (RE-ENERGIZE) include...
Published in Burns : journal of the International Society for Burn Injuries
Published in Burns : journal of the International Society for Burn Injuries
Proenkephalin A 119-159 (penKid) has been proposed as a sensitive biomarker of renal function. This study evaluated the association of concentrations of plasma penKid with death and risk of acute kidney injury (AKI) in severely ill burn patients. A prospective observational study in two centers with severely ill adult burn patients was conducted. T...
Published in Burns : journal of the International Society for Burn Injuries
Burn wounds continue to worsen after initial injury in a process known as burn conversion, which lasts about 3-5 days. It causes burn wounds to enlarge and deepen, leading to greater morbidity. Apoptosis is one of the factors contributing to the conversion of the zone of stasis into the zone of coagulation. Suppression of apoptosis has been associa...
Published in Burns : journal of the International Society for Burn Injuries
Published in Burns : journal of the International Society for Burn Injuries
Published in Burns : journal of the International Society for Burn Injuries
Published in Burns : journal of the International Society for Burn Injuries
The dysbiosis of gastrointestinal microbiome is an important reason for burn-induced intestinal injury. Clostridium butyricum (C.butyricum) and its production butyrate are beneficial for the homeostasis of intestinal microflora and suppression of inflammatory response. The roles of C.butyricum and butyrate in burn-induced intestinal injury were exp...