Newman, Lisa M. Trivedi, Mehul A. Bendlin, Barbara B. Ries, Michele L. Johnson, Sterling C.
Published in
Brain Imaging and Behavior
Voxel-based morphometry (VBM) was used to examine the relationship between gray matter (GM) volume and performance on two commonly used clinical neuropsychological measures of frontal lobe or executive function, the Trail Making Test part B (TrailsB) and the Controlled Oral Word Association Test (COWAT) in 221 cognitively healthy adults between the...
Arfanakis, Konstantinos Gui, Minzhi Tamhane, Ashish A. Carew, John D.
Published in
Brain Imaging and Behavior
The first neuropathological alterations in Alzheimer’s disease (AD) occur in the medial temporal lobes (MTLs), in the entorhinal cortex (EC), perforant pathway (PP), and hippocampus. The purpose of this study was to investigate the microstructural integrity, size, and T2-relaxation times of MTL structures in patients with AD and mild cognitive impa...
Griffith, H. Randall Okonkwo, Ozioma C. den Hollander, Jan A. Belue, Katherine Lanza, Sara Harrell, Lindy E. Brockington, John C. Clark, David G. Marson, Daniel C.
Published in
Brain Imaging and Behavior
Persons with Alzheimer’s disease (AD) demonstrate frank impairments in the performance of everyday functional abilities. However, the neuroanatomic and neuro-metabolic correlates of these functional deficits in mild AD are largely unknown. Using 3-Tesla proton magnetic resonance spectroscopy (1H-MRS) of the posterior cingulate gyrus in 14 patients ...
Saykin, Andrew J.
Published in
Brain Imaging and Behavior
David, Sean P. Munafò, Marcus R. Johansen-Berg, Heidi MacKillop, James Sweet, Lawrence H. Cohen, Ronald A. Niaura, Raymond Rogers, Robert D. Matthews, Paul M. Walton, Robert T.
...
Published in
Brain Imaging and Behavior
To achieve greater understanding of the brain mechanisms underlying nicotine craving in female smokers, we examined the influence of nicotine non-abstinence vs. acute nicotine abstinence on cue-elicited activation of the ventral striatum. Eight female smokers underwent an event-related functional magnetic resonance imaging (fMRI) paradigm presentin...
Oei, Nicole Y. L. Elzinga, Bernet M. Wolf, Oliver T. de Ruiter, Michiel B. Damoiseaux, Jessica S. Kuijer, Joost P. A. Veltman, Dick J. Scheltens, Philip Rombouts, Serge A. R. B.
Published in
Brain Imaging and Behavior
Glucocorticoids (GCs, cortisol in human) are associated with impairments in declarative memory retrieval. Brain regions hypothesized to mediate these effects are the hippocampus and prefrontal cortex (PFC). Our aim was to use fMRI in localizing the effects of GCs during declarative memory retrieval. Therefore, we tested memory retrieval in 21 young...
Marchand, William R. Lee, James N. Thatcher, John Thatcher, Grant William Jensen, Cody Starr, Jennifer
Published in
Brain Imaging and Behavior
The frontal–subcortical skeletomotor circuit is thought to be a motor processing network. However, the exact function of the circuit is poorly characterized. This fMRI study utilized a motor activation paradigm for both hands to probe circuit engagement and connectivity. Activation of the circuit decreased over time for the right hand, which sugges...
Wang, Yue Lin, Lotus Kuhl, Patricia Hirsch, Joy
Published in
Brain Imaging and Behavior
This study investigates the neuro-mechanisms underlying mathematical processing in native (L1) and nonnative (L2) languages. Using functional magnetic resonance imaging (fMRI), Mandarin Chinese learners of English were imaged while performing calculations, parity judgments and linguistic tasks in their L1 (Chinese) and L2 (English). Results show th...
Haut, Marc W. Moran, Maria T. Lancaster, Melissa A. Kuwabara, Hiroto Parsons, Michael W. Puce, Aina
Published in
Brain Imaging and Behavior
Cognitive reserve (CR) is a theoretical concept used to explain and study individual differences in cognitive symptom expression in neurological disease. In the absence of neurologic injury or demands on processing, compensatory and protective factors may be considered to represent cognitive capacity (CC), rather than cognitive reserve, per se. We ...
Reiterer, Susanne Erb, Michael Grodd, Wolfgang Wildgruber, Dirk
Published in
Brain Imaging and Behavior
Sound timbre and sound volume processing are basic auditory discrimination processes relevant for human language abilities. Regarding lateralization effects, the prevailing hypotheses ascribe timbre processing to the right hemisphere (RH). Recent experiments also point to a role of the RH for volume discrimination. We investigated the relevance of ...
