Published in Brain Imaging and Behavior
This study investigates the neuro-mechanisms underlying mathematical processing in native (L1) and nonnative (L2) languages. Using functional magnetic resonance imaging (fMRI), Mandarin Chinese learners of English were imaged while performing calculations, parity judgments and linguistic tasks in their L1 (Chinese) and L2 (English). Results show th...
Published in Brain Imaging and Behavior
The frontal–subcortical skeletomotor circuit is thought to be a motor processing network. However, the exact function of the circuit is poorly characterized. This fMRI study utilized a motor activation paradigm for both hands to probe circuit engagement and connectivity. Activation of the circuit decreased over time for the right hand, which sugges...
Published in Brain Imaging and Behavior
Glucocorticoids (GCs, cortisol in human) are associated with impairments in declarative memory retrieval. Brain regions hypothesized to mediate these effects are the hippocampus and prefrontal cortex (PFC). Our aim was to use fMRI in localizing the effects of GCs during declarative memory retrieval. Therefore, we tested memory retrieval in 21 young...
Published in Brain Imaging and Behavior
Published in Brain Imaging and Behavior
Persons with Alzheimer’s disease (AD) demonstrate frank impairments in the performance of everyday functional abilities. However, the neuroanatomic and neuro-metabolic correlates of these functional deficits in mild AD are largely unknown. Using 3-Tesla proton magnetic resonance spectroscopy (1H-MRS) of the posterior cingulate gyrus in 14 patients ...
Published in Brain Imaging and Behavior
The first neuropathological alterations in Alzheimer’s disease (AD) occur in the medial temporal lobes (MTLs), in the entorhinal cortex (EC), perforant pathway (PP), and hippocampus. The purpose of this study was to investigate the microstructural integrity, size, and T2-relaxation times of MTL structures in patients with AD and mild cognitive impa...
Published in Brain Imaging and Behavior
Voxel-based morphometry (VBM) was used to examine the relationship between gray matter (GM) volume and performance on two commonly used clinical neuropsychological measures of frontal lobe or executive function, the Trail Making Test part B (TrailsB) and the Controlled Oral Word Association Test (COWAT) in 221 cognitively healthy adults between the...
