Wemrell, Maria Bennet, Louise Merlo, Juan
Published in
BMJ Open Diabetes Research & Care
Objective Investigating demographic and socioeconomic factors as intersecting rather than as separate dimensions may improve our understanding of the heterogeneous distribution of type 2 diabetes in the population. However, this complexity has scarcely been investigated and we still do not know the accuracy of these factors for predicting type 2 di...
Castano Betancourt, Martha Cecilia Morais, Carolina Larissa Vannucci Nunes Lipay, Monica Aragão, Jordani de Azevedo e Souza Munhoz, Marcelo Gomes Machado, Eduardo Marchi, Evaldo
Published in
BMJ Open Diabetes Research & Care
Objective (1) To investigate differences in pain severity and its distribution between patients with and without diabetes mellitus (DM) in a population with advanced osteoarthritis (OA). (2) To explore the role of medication used for diabetes in these associations. Research design and methods This is a hospital-based cohort study of patients with a...
Singhal, Mukul Tan, Hiangkiat Coleman, Craig I Han, Michelle Nguyen, Chi Ingham, Michael
Published in
BMJ Open Diabetes Research & Care
Introduction This real-world study compared glycemic effectiveness, treatment durability, and treatment costs with canagliflozin 300 mg versus any dose of glucagon-like peptide-1 (GLP-1) receptor agonists in patients with type 2 diabetes mellitus (T2DM) in the USA. Research design and methods A retrospective cohort study using administrative claims...
Ásbjörnsdóttir, Björg Vestgaard, Marianne Ringholm, Lene MD Andersen, Lise Lotte Torvin Jensen, Dorte Møller Damm, Peter Mathiesen, Elisabeth R
Published in
BMJ Open Diabetes Research & Care
Objective To study how lifestyle coaching with motivational interviewing to improve adherence to healthy eating affects gestational weight gain and fetal growth in pregnant women with type 2 diabetes in a real-world setting. Research design and methods A cohort study including a prospective intervention cohort of consecutive, singleton pregnant, Da...
Yamanouchi, Masayuki Mori, Mikiro Hoshino, Junichi Kinowaki, Keiichi Fujii, Takeshi Ohashi, Kenichi Furuichi, Kengo Wada, Takashi Ubara, Yoshifumi
Published in
BMJ Open Diabetes Research & Care
Objective The predictive value of diabetic retinopathy on end-stage kidney disease (ESKD) has not been fully addressed in patients with type 2 diabetes and diabetic kidney disease. Research design and methods We studied 232 patients with type 2 diabetes and biopsy-proven diabetic kidney disease who were screened for diabetic retinopathy during the ...
Cesta, Carolyn E Cohen, Jacqueline M Pazzagli, Laura Bateman, Brian T Bröms, Gabriella Einarsdóttir, Kristjana Furu, Kari Havard, Alys Heino, Anna Hernandez-Diaz, Sonia
...
Published in
BMJ Open Diabetes Research & Care
Objective Diabetes in pregnancy and consequently the need for treatment with antidiabetic medication (ADM) has become increasingly prevalent. The prevalence and patterns of use of ADM in pregnancy from 2006 onward in seven different countries was assessed. Research design and methods Data sources included individually linked data from the nationwid...
Willemsen, Lisa Neele, Annette E van der Velden, Saskia Prange, Koen H M den Toom, Myrthe van Roomen, Cindy P A A Reiche, Myrthe E Griffith, Guillermo R Gijbels, Marion J J Lutgens, Esther
...
Published in
BMJ Open Diabetes Research & Care
Introduction Obesity is recognized as a risk factor for various microbial infections. The immune system, which is affected by obesity, plays an important role in the pathophysiology of these infections and other obesity-related comorbidities. Weight loss is considered the most obvious treatment for obesity. However, multiple studies suggest that th...
Xu, Liang Nagata, Naoto Chen, Guanliang Nagashimada, Mayumi Zhuge, Fen Ni, Yinhua Sakai, Yuriko Kaneko, Shuichi Ota, Tsuguhito
Published in
BMJ open diabetes research & care
We reported previously that empagliflozin-a sodium-glucose cotransporter (SGLT) 2 inhibitor-exhibited preventive effects against obesity. However, it was difficult to extrapolate these results to human subjects. Here, we performed a therapeutic study, which is more relevant to clinical situations in humans, to investigate antiobesity effects of emp...
Almog, Tal Kandel Kfir, Michal Levkovich, Hana Shlomai, Gadi Barshack, Iris Stienstra, Rinke Lustig, Yaniv Leikin Frenkel, Alicia Harari, Ayelet Bujanover, Yoram
...
Published in
BMJ open diabetes research & care
While extensive research revealed that interleukin (IL)-1β contributes to insulin resistance (IR) development, the role of IL-1α in obesity and IR was scarcely studied. Using control, whole body IL-1α knockout (KO) or myeloid-cell-specific IL-1α-deficient mice, we tested the hypothesis that IL-1α deficiency would protect against high-fat diet (HFD)...
Lin, Cheng-Wei Armstrong, David G Lin, Chia-Hung Liu, Pi-Hua Hung, Shih-Yuan Lee, Shu-Ru Huang, Chung-Huei Huang, Yu-Yao
Published in
BMJ open diabetes research & care
To study the prevalence and trends of lower extremity complications of diabetes over an 8-year period in a single nation. Nationwide data for people with type 2 diabetes (T2D) and diabetic foot complications (DFCs) were analyzed over an 8-year period (2007-2014) from National Health Insurance Research Database using the International Classification...
