Nimmy John, T. Subha Dharmapalan, Puthankattil Ramshekhar Menon, N.
Published in
BMC Neuroscience
BackgroundIn this study, nonlinear based time–frequency (TF) and time domain investigations are employed for the analysis of electroencephalogram (EEG) signals of mild cognitive impairment–Alzheimer’s disease (MCI–AD) patients and healthy controls. This study attempts to comprehend the cognitive decline of MCI–AD under both resting and cognitive ta...
Meusel, Liesel-Ann C. Greenwood, Carol E. Maione, Andrea Tchistiakova, Ekaterina MacIntosh, Bradley J. Anderson, Nicole D.
Published in
BMC Neuroscience
BackgroundCardiovascular conditions contribute to brain volume loss, reduced cerebrovascular health, and increased dementia risk in aging adults. Altered hippocampal connectivity has also been observed in individuals with cardiovascular conditions, yet the functional consequences of these changes remain unclear. In the present study, we collected f...
Koutsoumpa, Andriana Papatheodoropoulos, Costas
Published in
BMC Neuroscience
BackgroundThe functional heterogeneity of the hippocampus along its longitudinal axis at the level of behavior is an established concept; however, the neurobiological mechanisms are still unknown. Diversifications in the functioning of intrinsic hippocampal circuitry including short-term dynamics of synaptic inputs and neuronal output, that are imp...
Thiele, Robert H. Osuru, Hari P. Paila, Umadevi Ikeda, Keita Zuo, Zhiyi
Published in
BMC Neuroscience
BackgroundEmerging data suggests that volatile anesthetic agents may have organ protection properties in the setting of critical illness. The purpose of this study was to better understand the effect of inflammation on cerebral subcellular energetics in animals exposed to two different anesthetic agents—a GABA agonist (propofol) and a volatile agen...
Huang, Hui-Ting Tsai, Sheng-Feng Wu, Hung-Tsung Huang, Hsin-Ying Hsieh, Han-Hsueh Kuo, Yu-Ming Chen, Po-See Yang, Chung-Shi Tzeng, Shun-Fen
Published in
BMC Neuroscience
BackgroundHypothalamic inflammation including astrogliosis and microglia activation occurs after intake of high fat diet (HFD) in rodent models or in obese individuals. However, the effect of chronic HFD feeding on oligodendrocytes (OLGs), a myelin-producing glial population in the central nervous system (CNS), remains unclear. In this study, we us...
Luo, Peng Dong, Jianghui Qi, Jian Zhang, Yi Liu, Xiaolin Zhong, Yingchun Xian, Cory J. Wang, Liping
Published in
BMC Neuroscience
BackgroundThree-dimensional (3D) reconstruction of human peripheral nerves, as a useful tool to understand the nerve internal information and functional basis, has become an important area of research in the peripheral nerve field.MethodsIn this study, we proposed a two-dimensional (2D) Karnovsky–Roots toluidine blue ponceau 2R (K-B-2R) staining me...
Liu, Chang Pu, Weidan Wu, Guowei Zhao, Jie Xue, Zhimin
Published in
BMC Neuroscience
BackgroundDistinctive patterns of functional connectivity (FC) abnormalities in neural circuitry has been reported in patients with bipolar depression (BD) and unipolar depression (UD). However, it is unclear that whether this distinct functional connectivity patterns are diagnosis specific between BD and UD. This study aimed to compare patterns of...
Yan, Jinyuan Yang, Zhongshan Zhao, Ninghui Li, Zhiwei Cao, Xia
Published in
BMC Neuroscience
BackgroundRecently, the use of traditional Chinese medicine (TCM) has become more generally accepted, including by the Food and Drug Administration. To expand the use of TCM worldwide, it is important to study the molecular mechanisms by which TCM and its active ingredients produce effects. Gastrodin is an active ingredient from Gastrodia elata Blu...
Kostic, Draginja Carlson, Regina Henke, Diana Rohn, Karl Tipold, Andrea
Published in
BMC Neuroscience
BackgroundEpilepsy is a common neurological disease in dogs affecting approximately 0.6–0.75% of the canine population. There is much evidence of neuroinflammation presence in epilepsy, creating new possibilities for the treatment of the disease. An increased expression of interleukin-1 beta (IL-1β) was reported in epileptogenic foci. We hypothesiz...
Bui, Michelle Shyong, Jennifer Lutz, Eleanor K. Yang, Ting Li, Ming Truong, Kenneth Arvidson, Ryan Buchman, Anna Riffell, Jeffrey A. Akbari, Omar S.
...
Published in
BMC Neuroscience
BackgroundThe mosquito Aedes aegypti has a wide variety of sensory pathways that have supported its success as a species as well as a highly competent vector of numerous debilitating infectious pathogens. Investigations into mosquito sensory systems and their effects on behavior are valuable resources for the advancement of mosquito control strateg...
