Lin, Weihong Ezekwe, Ejiofor AD Jr Zhao, Zhen Liman, Emily R Restrepo, Diego
Published in
BMC Neuroscience
BackgroundThe main olfactory epithelium (MOE) in the nasal cavity detects a variety of air borne molecules that provide information regarding the presence of food, predators and other relevant social and environmental factors. Within the epithelium are ciliated sensory neurons, supporting cells, basal cells and microvillous cells, each of which is ...
Tu, Ewen Chen, Qiong Tan, Li Wang, Yan
Published in
BMC Neuroscience
BackgroundCerebral stroke occurs following ischemic and hemorrhagic lesions in the brain. Survival and recovery of stroke patients depend on the severity of the initial injury but also the therapeutic approaches applied for emergent lifesaving and continuing post-stroke management. Dl-3-n-Butylphthalide (NBP), an active compound derived from Chines...
Rajalingam, Dhaksshaginy Nymoen, Ingeborg Jacobsen, Daniel Pitz Eriksen, Mina Baarnes Dissen, Erik Nielsen, Morten Birkeland Einarsen, Ståle Valvatne Gjerstad, Johannes
Published in
BMC Neuroscience
BackgroundPrevious studies suggest that persistent exposure to social stress in mammals may be associated with multiple physiological effects. Here, we examine the effects of social stress in rats, i.e. repeated social defeat, on behavior, hypothalamic–pituitary–adrenal (HPA)-axis and immune system.MethodsA resident-intruder paradigm, where an intr...
Rosenberg, Nicole Ihme, Klas Lichev, Vladimir Sacher, Julia Rufer, Michael Grabe, Hans Jörgen Kugel, Harald Pampel, André Lepsien, Jöran Kersting, Anette
...
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BMC Neuroscience
BackgroundAlexithymia is a personality trait characterized by difficulties identifying and describing feelings, an externally oriented style of thinking, and a reduced inclination to imagination. Previous research has shown deficits in the recognition of emotional facial expressions in alexithymia and reductions of brain responsivity to emotional s...
Seno, Soichiro Wang, Jun Cao, Suyi Saraswati, Manda Park, Sharon Simoni, Jan Ma, Li Soltys, Bohdan Hsia, Carleton J. C. Koehler, Raymond C.
...
Published in
BMC Neuroscience
BackgroundPolynitroxylated PEGylated hemoglobin (PNPH, aka SanFlow) possesses superoxide dismutase/catalase mimetic activities that may directly protect the brain from oxidative stress. Stabilization of PNPH with bound carbon monoxide prevents methemoglobin formation during storage and permits it to serve as a carbon monoxide donor. We determined w...
Zhang, Ke-Ying Rui, Gang Zhang, Jun-Ping Guo, Ling An, Guang-Zhou Lin, Jia-Jin He, Wei Ding, Gui-Rong
Published in
BMC Neuroscience
BackgroundTranscranial direct current stimulation (tDCS) is a non-invasive brain modulation technique that has been proved to exert beneficial effects in the acute phase of stroke. To explore the underlying mechanism, we investigated the neuroprotective effects of cathodal tDCS on brain injury caused by middle cerebral artery occlusion (MCAO).Resul...
Li, Gang Huang, Shan Xu, Wanxiu Jiao, Weidong Jiang, Yonghua Gao, Zhao Zhang, Jianhua
Published in
BMC Neuroscience
BackgroundMental fatigue is usually caused by long-term cognitive activities, mainly manifested as drowsiness, difficulty in concentrating, decreased alertness, disordered thinking, slow reaction, lethargy, reduced work efficiency, error-prone and so on. Mental fatigue has become a widespread sub-health condition, and has a serious impact on the co...
Ueno, Hiroshi Suemitsu, Shunsuke Murakami, Shinji Kitamura, Naoya Wani, Kenta Takahashi, Yu Matsumoto, Yosuke Okamoto, Motoi Ishihara, Takeshi
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BMC Neuroscience
BackgroundEmpathy refers to the ability to recognise and share emotions with others. Several research groups have recognised observational fear in mice as a useful behavioural model for assessing their ability to empathise. However, in these observation systems, it remains unclear whether the observer mouse truly recognises the movements of, and em...
Jiang, Ya Bai, Xue Li, Ting-Ting AL-Hawwas, Mohammed Jin, Yuan Zou, Yu Hu, Yue Liu, Lin-Yi Zhang, Ying Liu, Qing
...
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BMC Neuroscience
BackgroundNeonatal hypoxic-ischemic encephalopathy (HIE) represents as a major cause of neonatal morbidity and mortality. However, the underlying molecular mechanisms in brain damage are still not fully elucidated. This study was conducted to determine the specific potential molecular mechanism in the hypoxic-ischemic induced cerebral injury.Method...
Zhang, Tao Niu, Jiahui Wang, Yaxian Yan, Junying Hu, Wen Mi, Daguo
Published in
BMC Neuroscience
An amendment to this paper has been published and can be accessed via the original article.