Xu, Feng-bo Cheng, Hong Yue, Tong Ye, Nan Zhang, He-jia Chen, Yi-pu
Published in
BMC Nephrology
BackgroundAcute kidney injury (AKI) is a major complication of acute myocardial infarction(AMI), which can significantly increase mortality. This study is to analyze the related risk factors and establish a prediction score of acute kidney injury in order to take early measurement for prevention.MethodsThe medical records of 6014 hospitalized patie...
Pedrós, Consuelo Ávila, Mónica Gómez-Lumbreras, Ainhoa Manríquez, Marcela Morros, Rosa
Published in
BMC Nephrology
BackgroundThe use of metformin in patients with type 2 diabetes mellitus has been associated with lactic acidosis. However, the information available in patients with moderate-severe chronic kidney disease is scarce.MethodsThe ALIMAR-C2 study is a case-control study to assess the association between metformin and lactic acidosis in patients with ty...
Kuki, Atsumi Tanaka, Kentaro Kushiyama, Akifumi Tanaka, Yoshihide Motonishi, Shuta Sugano, Yasuji Furuya, Toru Ozawa, Takashi
Published in
BMC Nephrology
BackgroundGait speed (GS) and handgrip strength (HGS), both factors associated with frailty and sarcopenia, are reportedly associated with CV events in the general population. However, little is known about the impact of these factors on the outcome of patients on dialysis. This study aimed to evaluate whether evaluation of GS and HGS could be asso...
Cano-Megías, Marta Guisado-Vasco, Pablo Bouarich, Hanane de Arriba-de la Fuente, Gabriel de Sequera-Ortiz, Patricia Álvarez-Sanz, Concepción Rodríguez-Puyol, Diego
Published in
BMC Nephrology
BackgroundPatients with advanced chronic kidney disease (CKD) exhibit higher prevalence of coronary artery calcification (CaC) than general population. CaC has been proposed as a risk factor for mortality in end-stage CKD, but most studies in the field are based on short-term follow-up.MethodsWe conducted a cohort, 10-year prospective longitudinal ...
Coronado Daza, Jorge Vernooij, Robin W. M. Salas, Karla Osorio, Dimelza Urrútia Cuchí, Gerard
Published in
BMC Nephrology
BackgroundChronic kidney disease (CKD) is a worldwide public health problem. Clinical practice guidelines (CPGs) are being developed and implemented in order to improve clinical practice related to the detection and treatment of CKD. The objective of our study was to evaluate the quality of CPGs regarding the CKD and to examine whether there are fa...
Xia, Wenli Gao, Bixia Duan, Lin Li, Yan Wen, Yubing Chen, Limeng Li, Xuemei Zheng, Falei Li, Mingxi
Published in
BMC Nephrology
BackgroundTo evaluate renal expression of C4d, a complement component in the classical/mannose binding lectin (MBL) pathway, in patients with primary Sjögren’s syndrome (pSS)-associated renal impairments.MethodsWe retrospectively reviewed the clinical and pathological data from 39 patients with pSS presenting with renal impairments. C4d was examine...
Ichinose, Mayuri Sasagawa, Naru Chiba, Tetsuo Toyama, Katsuhide Kayamori, Yuzo Kang, Dongchon
Published in
BMC Nephrology
BackgroundThrombophilia due to protein C (PC) and protein S (PS) deficiencies is highly prevalent among patients with stage 5 chronic kidney disease and is reported to arise due to extracorporeal circulation during hemodialysis (HD). This study aimed to evaluate the relationship between HD treatment and thrombophilia.MethodsA total of 114 Japanese ...
Mathur, Amit K. Chang, Yu-Hui Steidley, D. Eric Heilman, Raymond L. Wasif, Nabil Etzioni, David Reddy, Kunam S. Moss, Adyr A.
Published in
BMC Nephrology
BackgroundKidney transplant (KT) patients presenting with cardiovascular (CVD) events are being managed increasingly in non-transplant facilities. We aimed to identify drivers of mortality and costs, including transplant hospital status.MethodsData from the 2009–2011 Nationwide Inpatient Sample, the American Hospital Association, and Hospital Compa...
Dai, Rufeng Liu, Haimei Han, Xinli Liu, Junchao Zhai, Yihui Rao, Jia Shen, Qian Xu, Hong
Published in
BMC Nephrology
BackgroundAngiopoietin-like-3 (Angptl3) knockout is known for its protective effects on podocyte injury and proteinuria in the early stage of adriamycin (ADR) nephropathy. The current study re-evaluated the renoprotective effect of Angptl3 knockout in chronic ADR nephropathy and attempted to explore the mechanism underlying the effect associated wi...
Ryu, Hyunjin Cho, Hyunjeong Oh, Yun Kyu Joo, Kwon Wook Kim, Yon Su Ahn, Curie Han, Seung Seok
Published in
BMC Nephrology
BackgroundVitamin D deficiency is an important health concern because it is related to several comorbidities and mortality. However, its relationship with the risk of hematuria remains undetermined in the general population. In this study, we analyzed the association between vitamin D deficiency and hematuria.MethodsWe conducted cross-sectional ana...
