Menne, Jan Delmas, Yahsou Fakhouri, Fadi Licht, Christoph Lommelé, Åsa Minetti, Enrico E. Provôt, François Rondeau, Eric Sheerin, Neil S. Wang, Jimmy
...
Published in
BMC Nephrology
BackgroundThere are limited long-term outcome data in eculizumab-treated patients with atypical hemolytic uremic syndrome (aHUS). We report final results from the largest prospective, observational, multicenter study of patients with aHUS treated with eculizumab.MethodsPatients with aHUS who participated in any of five parent eculizumab trials and ...
Tannor, Elliot K. Norman, Betty R. Adusei, Kwame K. Sarfo, Fred S. Davids, Mogamat R. Bedu-Addo, George
Published in
BMC Nephrology
BackgroundThe prevalence of chronic kidney disease (CKD) is increasing worldwide and in Africa. Health related quality of life (QOL) has become an essential outcome measure for patients with CKD and end stage renal disease (ESRD). There is growing interest worldwide in QOL of CKD patients but paucity of data in Ghana. This study sought to assess QO...
Miyamoto, Yasunori Hirayama, Kouichi Maruyama, Hiroshi Ohgi, Kentaro Takayasu, Mamiko Shimohata, Homare Kobayashi, Masaki
Published in
BMC Nephrology
BackgroundThymic hyperplasia and thymic epithelial tumor (thymoma) have been associated with a variety of autoimmune diseases. Renal involvement has been reported in patients with thymoma. Minimal change disease and membranous nephropathy are frequently observed in glomerular lesions of thymoma patients, but ANCA-associated renal vasculitis is rare...
Domanski, Leszek Kłoda, Karolina Patrzyk, Maciej Wisniewska, Magda Safranow, Krzysztof Sienko, Jerzy Sulikowski, Tadeusz Staniszewska, Marzena Pawlik, Andrzej
Published in
BMC Nephrology
BackgroundInterleukin 17 is a proinflammatory cytokine involved in immune response after allograft transplantation. IL-17 family of proinflammatory cytokines includes IL-17A and IL-17F. Previous studies have demonstrated that the rs2275913 IL17A and the rs11465553 IL17F gene polymorphism are associated with kidney allograft function. Because of the...
Tanaka, Mai Nishiwaki, Hiroki Kado, Hiroshi Doi, Yohei Ihoriya, Chieko Omae, Kenji Tamagaki, Keiichi
Published in
BMC Nephrology
BackgroundLittle is known about salt taste dysfunction among hemodialysis (HD) patients. This study aimed to elucidate the prevalence of salt taste dysfunction and its relationship with interdialytic weight gain (IDWG) among HD patients.MethodsA single-center cross-sectional study involving 99 maintenance HD patients was conducted in September 2015...
Takahashi, Ryohei Shinoda, Kazunobu Ishida, Takashi Hamamoto, Yasuo Morita, Shinya Akita, Hirotaka Kitaoka, Sotaro Tamaki, Satoshi Asanuma, Hiroshi Yoshida, Tadashi
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Published in
BMC Nephrology
BackgroundGastrointestinal stromal tumors (GISTs) in transplant recipients are very rare and only a handful of cases have been reported to date. Here we present the first known case of a huge GIST in a kidney transplant recipient with perforation of small intestine.Case presentationA 64-year-old male presented at our hospital with right colic pain;...
Xia, Yuan-Yuan Bu, Ru Cai, Guang-Yan Zhang, Xue-Guang Duan, Shu-Wei Wu, Jie Wu, Di Chen, Xiang-Mei
Published in
BMC Nephrology
BackgroundThis study aimed to evaluate the value of urinary angiostatin levels for assessing disease severity and progression of IgA nephropathy (IgAN).MethodsUrinary angiostatin was identified as one of the distinct proteins in samples of patients with IgAN analyzed by Raybiotech protein array, and further confirmed by enzyme-linked immunosorbent ...
Kim, Hyo Jin Lee, Joongyub Chae, Dong-Wan Lee, Kyu-Beck Sung, Su Ah Yoo, Tae-Hyun Han, Seung Hyeok Ahn, Curie Oh, Kook-Hwan
Published in
BMC Nephrology
BackgroundMetabolic syndrome (MS) is prevalent in chronic kidney disease (CKD). Klotho, a protein linked to aging, is closely associated with CKD. Each component of MS and klotho has an association. However, little is known about the association between klotho and MS per se. We investigated the association between serum klotho levels and MS using b...
Russ, Philipp Russwurm, Martin Kortus-Goetze, Birgit Hoyer, Joachim Kamalanabhaiah, Sahana
Published in
BMC Nephrology
BackgroundCalciphylaxis is a life threatening complication in renal patients. Of great importance is the identification of concomitant factors for calciphylaxis. Due to the variability of clinical presentation the evaluation of such factors may be obscured when calciphylaxis diagnosis is based just on clinical features. We aimed to characterize ass...
Seki, Makiko Nakayama, Masaru Sakoh, Teppei Yoshitomi, Ryota Fukui, Akiko Katafuchi, Eisuke Tsuda, Susumu Nakano, Toshiaki Tsuruya, Kazuhiko Kitazono, Takanari
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Published in
BMC Nephrology
BackgroundBlood urea nitrogen (BUN) is one of the substances that affects the calculated serum osmolality (cSosm). A previous study demonstrated that BUN and cSosm were independently associated with the development of chronic kidney disease (CKD) in patients with preserved kidney function. In advanced CKD stages, there is a concomitant increase in ...
