Chatrenet, Antoine Beaune, Bruno Fois, Antioco Pouliquen, Camille Audebrand, Jean-Michel Torreggiani, Massimo Paris, Damien Durand, Sylvain Piccoli, Giorgina Barbara
Published in
BMC Nephrology
BackgroundChronic Kidney Disease (CKD) is associated with reduced muscular strength resulting in profound fatigue. The physiopathology of these changes, their prevalence and evolution are still debated. Moreover, we have little data on elderly CKD patients. The present study protocol aims to 1) quantify the prevalence of low muscle strength (dynape...
Bahougne, Thibault Olagne, Jérome Munch, Marion Braun-Parvez, Laura Chenard, Marie-Pierrette Frémeaux-Bacchi, Véronique Caillard, Sophie Baltzinger, Philippe Greget, Michel Kessler, Laurence
...
Published in
BMC Nephrology
BackgroundWe here report on the first observation of a C3 mutation that is related to atypical hemolytic and uremic syndrome (aHUS), which occurred in a pancreatic islet transplant patient. Immunosuppressive treatments, such as calcineurin inhibitors, have been linked to undesirable effects like nephrotoxicity.Case presentationA 40-year-old man wit...
Olivier, Valerie Dunyach-Remy, Catherine Corbeau, Pierre Cristol, Jean-Paul Sutra, Thibault Burtey, Stephane Lavigne, Jean-Philippe Moranne, Olivier
Published in
BMC Nephrology
BackgroundThe relationships between digestive bacterial translocation, uremic toxins, oxidative stress and microinflammation in a population of chronic kidney disease (CKD) patients without metabolic nor inflammatory disease are unknown.MethodsBacterial translocation, uremic toxins, oxidative stress, and inflammation were assessed by measuring plas...
Yu, Shasha Guo, Xiaofan Li, Guang Xiao Yang, Hongmei Zheng, Liqiang Sun, Yingxian
Published in
BMC Nephrology
BackgroundMetabolic healthy obesity (MHO), a phenotype of obesity, seems to be associated with a lower risk of cardiovascular disease. However, MHO has a close relationship with a higher incidence of metabolic syndrome and diabetes. This study aimed to investigate the prevalence of MHO at baseline, the changes in the obese metabolic phenotype at fo...
Huang, Yi Li, Xiao-Juan Li, Yue-Qiang Dai, Wei Shao, Tiffany Liu, Wei-Yong Han, Min Xu, Gang Liu, Liu
Published in
BMC Nephrology
BackgroundSince the Coronavirus Disease 2019 (COVID-19) outbreak, there is accumulating data on the clinical characteristics, treatment strategies and prognosis of COVID-19 in patients with concurrent renal disease. Postmortem investigations reveal renal involvement in COVID-19, and most recently, several biopsy researches reveal that acute tubular...
Zhou, Qianyun Zhang, Yuanyuan Zhou, Guangping Zhu, Jihong
Published in
BMC Nephrology
BackgroundTAFRO syndrome is a clinical subtype of idiopathic multicentric Castleman disease (iMCD) that is characterized by thrombocytopenia, anasarca, fever, reticulin myelofibrosis (or renal dysfunction), and organomegaly. TAFRO syndrome has only recently been described, and many clinicians are unaware of this disease, leading to delays in diagno...
Target, Natalia Courivaud, Cécile Michel, Pierre Antoine Daoud, Salima Thomas, Michel
Published in
BMC Nephrology
BackgroundHome haemodialysis (HHD), has shown improved clinical outcomes, as well as a better quality of life, compared to conventional in-centre haemodialysis (ICHD) but still has a global low prevalence among end-stage renal disease patients. Haemodialysis (HD) patients tend to be sedentary but only few studies, mainly in North American ICHD pati...
Good-Weber, Miriam Roos, Malgorzata Mueller, Thomas F. Rüsi, Barbara Fehr, Thomas
Published in
BMC Nephrology
BackgroundKidney allograft survival continuously improved with introduction of novel immunosuppressants. However, also immunologically challenging transplants (blood group incompatibility and sensitized recipients) increase. Between 2006 and 2008, a new tailored immunosuppression scheme for kidney transplantation was implemented at the University H...
Ferreira, Emily de Souza Moreira, Tiago Ricardo da Silva, Rodrigo Gomes da Costa, Glauce Dias da Silva, Luciana Saraiva Cavalier, Samantha Bicalho de Oliveira Silva, Beatriz Oliveira Dias, Heloísa Helena Borges, Luiza Delazari Machado, Juliana Costa
...
Published in
BMC Nephrology
Backgroundoptimal management of end-stage renal disease (ESRD) in hemodialysis (HD) patients should be more studied because it is a serious risk factor for mortality, being considered an unquestionable global priority.Methodswe performed a retrospective cohort study from the Nephrology Service in Brazil evaluating the survival of patients with ESRD...
Patschan, Daniel Schwarze, Katrin Tampe, Björn Becker, Jan Ulrich Hakroush, Samy Ritter, Oliver Patschan, Susann Müller, Gerhard Anton
Published in
BMC Nephrology
BackgroundEndothelial Progenitor Cells have been shown as effective tool in experimental AKI. Several pharmacological strategies for improving EPC-mediated AKI protection were identified in recent years. Aim of the current study was to analyze consequences of constitutive Atg5 activation in murine EPCs, utilized for AKI therapy.MethodsIschemic AKI ...
