Ciliberti, Maria Paola Carbonara, Roberta Grillo, Antonietta Leo, Anna Maria Lolli, Ivan Ostuni, Carmela Troiani, Laura Turi, Barbara Vallarelli, Simona Sardaro, Angela
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Published in
BMC Cancer
BackgroundSkin metastases from pancreatic neuroendocrine carcinoma (PNEC) are rare and their palliative treatment is challenging. We report our experience in the multimodal management of one of the few reported cases of metastatic PNEC with multiple visceral and subcutaneous secondary lesions, focusing on the effectiveness of palliative radiotherap...
Dai, Wei Fang Beca, Jaclyn M. Croxford, Ruth Isaranawatchai, Wanrudee Menjak, Ines B. Petrella, Teresa M. Mittmann, Nicole Earle, Craig C. Gavura, Scott Hanna, Timothy P.
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Published in
BMC Cancer
BackgroundFor novel cancer treatments, effectiveness in clinical practice is not always aligned with clinical efficacy results. As such it is important to understand a treatment’s real-world effectiveness. We examined real-world population-based comparative effectiveness of second-line ipilimumab versus non-ipilimumab treatments (chemotherapy or ta...
Nakajima, Tomoyuki Uehara, Takeshi Iwaya, Mai Kobayashi, Yukihiro Maruyama, Yasuhiro Ota, Hiroyoshi
Published in
BMC Cancer
BackgroundLeucine-rich repeat-containing G-protein-coupled receptor 5 (LGR5) is a promising intestinal stem cell and carcinoma stem cell marker. We examined the relationship between mismatch repair (MMR) protein deficiency and LGR5 expression in poorly differentiated (PD) colorectal carcinoma (CRC).MethodsIn 29 cases of PD-CRC, deficiencies in MMR ...
Liu, Denghua Cai, Jing Gao, Aiwei Wang, Zehua Cai, Liqiong
Published in
BMC Cancer
BackgroundThe aim of this systematic review and meta-analysis was to compare overall survival and disease-free survival after fertility sparing surgery (FSS) vs radical surgery in stage 1 epithelial ovarian cancer (EOC).MethodsA systematic literature search of PubMed, BioMed Central, Scopus, CENTRAL (Cochrane Central Register of Controlled Trials) ...
Li, Xueying Yu, Weiming Liang, Chao Xu, Yuan Zhang, Miaozun Ding, Xiaoyun Cai, Xianlei
Published in
BMC Cancer
BackgroundColon adenocarcinoma (COAD) is one of the most lethal cancers. It is particularly important to accurately predict prognosis and to provide individualized treatment. Several lines of evidence suggest that genetic factors and clinicopathological characteristics are related to cancer onset and progression. The aim of this study was to identi...
Tamura, Ryota Morimoto, Yukina Kosugi, Kenzo Sato, Mizuto Oishi, Yumiko Ueda, Ryo Kikuchi, Ryogo Nagashima, Hideaki Hikichi, Tetsuro Noji, Shinobu
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Published in
BMC Cancer
Following publication of the original article [1], the authors reported an error in the author group.
Boegeholz, J. Brueggen, C. S. Pauli, C. Dimitriou, F. Haralambieva, E. Dummer, R. Manz, M. G. Widmer, C. C.
Published in
BMC Cancer
BackgroundCancer immunotherapy via immune-checkpoint inhibition (ICI) by antibodies against cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) and cell death protein 1 (PD-1) have significantly improved the outcome of metastasized melanoma and of a rapidly increasing number of other cancer types. The anti-tumor effect is often accompanied by immu...
Xu, Jiasheng Liao, Kaili Fu, Zhonghua Xiong, Zhenfang
Published in
BMC Cancer
BackgroundTo screen and analyze differentially expressed genes in pancreatic carcinoma tissues taken from Mongolian and Han patients by Affymetrix Genechip. Methods: Pancreatic ductal cell carcinoma tissues were collected from the Mongolian and Han patients undergoing resection in the Second Affiliated Hospital of Nanchang University from March 201...
Tuoheti, Zulipiyamu Han, Lili Husaiyin, Sulaiya Liu, Xiaoxi Ma, Chunhua Niyazi, Mayinuer
Published in
BMC Cancer
BackgroundRIPK1 (receptor-interacting protein kinase-1) plays a role in cancer development, whereas no clear studies focused on the cervical cancer. The objective of this study was to evaluate the relationship between RIPK1 polymorphisms and cervical cancer risk among the Uyghur population.MethodsWe performed a case-control study including 342 cerv...
Dizanzo, María Paula Marziali, Federico Brunet Avalos, Clarisse Bugnon Valdano, Marina Leiva, Santiago Cavatorta, Ana Laura Gardiol, Daniela
Published in
BMC Cancer
BackgroundPersistent infection with high-risk Human Papillomavirus (HPVs) is associated with the development of cervical cancer. The transforming capacity of these viruses relies on the cooperative action of the E6 and E7 viral oncoproteins. Among the oncogenic activities of E6, the interaction and interference with cell polarity PDZ proteins have ...
