Kim, Joonseok Budoff, Matthew J Nasir, Khurram Wong, Nathan D Yeboah, Joseph Al-Mallah, Mouaz H Shea, Steve Dardari, Zeina A Blumenthal, Roger S Blaha, Michael J
...
Published in
Atherosclerosis
TAC is associated with incident CVD and all-cause mortality. Nevertheless, the independent 10-year prognostic value of TAC in individuals with CAC = 0 beyond traditional risk factors is not well established. 3415 MESA participants with baseline CAC = 0 were followed for CHD, CVD events and all-cause mortality. TAC was measured in the ascending and ...
Gambardella, Jessica Sardu, Celestino Sacra, Cosimo Del Giudice, Carmine Santulli, Gaetano
Published in
Atherosclerosis
Ladwig, Karl-Heinz Baumert, Jens Marten-Mittag, Birgitt Lukaschek, Karoline Johar, Hamimatunnisa Fang, Xioayan Ronel, Joram Meisinger, Christa Peters, Annette
Published in
Atherosclerosis
Depressed mood and exhaustion (DEEX) have gained attention as a risk predictor for cardiovascular disease (CVD). Studies to estimate its ranking in prediction models are sparse. The study included 3428 men aged 45-74 years who participated in one of three population-based MONICA/KORA Augsburg surveys conducted between 1984 and 1995. Within a follow...
Chen, Jing Zhang, Jing Yang, Jian Xu, Lin Hu, Qi Xu, Changwu Yang, Shuo Jiang, Hong
Published in
Atherosclerosis
Deregulation of histone demethylase KDM3a, an important regulator for H3K9 methylation, is correlated with obesity and abnormal metabolism in rodent models. However, the function of KDM3a in vascular remodeling under diabetic condition is unknown. Adenoviruses expressing KDM3a and lentiviruses expressing KDM3a-targeting siRNA were generated to stud...
Cheezum, Michael K Kim, Alexander Bittencourt, Marcio S Kassop, David Nissen, Alexander Thomas, Dustin M Nguyen, Binh Glynn, Robert J Shah, Nishant R Villines, Todd C
...
Published in
Atherosclerosis
The impact of tobacco use and cessation on atherogenesis remains unclear. We aimed to study the association of tobacco use and prior cessation with the presence, extent and severity of atherosclerosis on coronary computed tomographic angiography (CTA). We examined 1798 consecutive symptomatic patients without known coronary artery disease (CAD) ref...
Kanemura, Noriyoshi Shibata, Rei Ohashi, Koji Ogawa, Hayato Hiramatsu-Ito, Mizuho Enomoto, Takashi Yuasa, Daisuke Ito, Masanori Hayakawa, Satoko Otaka, Naoya
...
Published in
Atherosclerosis
These findings indicate that CTRP1 functions to prevent the development of pathological vascular remodeling by reducing VSMC growth through the cAMP-dependent pathway.
Ammirati, Enrico Fogacci, Federica
Published in
Atherosclerosis
Osawa, Kazuhiro Nakanishi, Rine Budoff, Matthew J
Published in
Atherosclerosis
Cerebrovascular disease (CVA) is one of the most prevalent causes of death and disability in the United States, and its primary prevention is crucial. For the primary prevention of CVA, it is commonly recommended that all adults should initially undergo an office-based traditional risk assessment using established predictive models, such as the Fra...
Panes, Olga González, César Hidalgo, Patricia Valderas, Juan P Acevedo, Mónica Contreras, Susana Sánchez, Ximena Pereira, Jaime Rigotti, Attilio Mezzano, Diego
...
Published in
Atherosclerosis
High plasma LDL-cholesterol (LDL-C) and platelet responses have major pathogenic roles in atherothrombosis. Thus, statins and anti-platelet drugs constitute mainstays in cardiovascular prevention/treatment. However, the role of platelet tissue factor-dependent procoagulant activity (TF-PCA) has remained unexplored in hypercholesterolemia. We aimed ...
Shahid, Saleem Ullah Shabana Cooper, Jackie A Beaney, Katherine E Li, Kawah Rehman, Abdul Humphries, Steve E
Published in
Atherosclerosis
The GRS was quantitatively associated with CAD risk and showed association with blood lipid levels, suggesting that the mechanism of these variants is likely to be, in part at least, through creating an atherogenic lipid profile in subjects carrying high numbers of risk alleles.
