Published in Asian Biomedicine
Background Leptospirosis, caused by pathogenic Leptospira spp., is a widespread zoonotic disease worldwide. Early diagnosis is required for proper patient management and reducing leptospirosis morbidity and mortality. Objective To summarize current literature regarding commonly used and new promising molecular approaches to Leptospira detection and...
Published in Asian Biomedicine
Background Leptospirosis, caused by pathogenic Leptospira spp., is a widespread zoonotic disease worldwide. Early diagnosis is required for proper patient management and reducing leptospirosis morbidity and mortality. Objective To summarize current literature regarding commonly used and new promising molecular approaches to Leptospira detection and...
Published in Asian Biomedicine
Background Atmospheric plasma jet has different medical applications due to its low temperature at room temperature. In recent years, the effect of nonthermal plasmas on cancer cells has been studied, and it has been shown that this type of plasma has anti-proliferative effects on cancer cells. Objectives To design a plasma jet handpiece, which can...
Published in Asian Biomedicine
BackgroundWhile the assisted reproductive technology (ART) relieves the burden of infertility in many couples, it presents significant public health challenges due to the substantial risk for multiple birth delivery and preterm birth, which are associated with poor maternal and fetal health outcomes. For this reason, it is important to monitor the ...
Published in Asian Biomedicine
BackgroundComplications in periodontitis and other systemic infections related to Porphyromonas gingivalis poses a serious impediment in the treatment process. This leads to the search of novel target proteins to develop newer drugs against P. gingivalis. Prolyl tripeptidyl peptidase (ptp-A) seem to be a vital protein in P. gingivalis virulence and...
Published in Asian Biomedicine
BackgroundTrauma is a major cause of death in young adults. The mortality rate is one of the key performance indices of trauma centers. ObjectiveTo demonstrate a mortality rate, cause of death, and cause of nonpreventable death in a level-1 trauma center in Thailand. MethodsThere was a retrospective study of the death cases from a trauma registry. ...
Published in Asian Biomedicine
BackgroundAutophagy and ubiquitin–proteasome (UPS) are two main degradation systems for intracellular proteins. They are essential for homeostasis of neurons during normal and pathological conditions, but their changes after nerve injury remain unclear. ObjectiveTo examine the protein expression of autophagy and UPS in the dorsal root ganglia (DRG)...
Published in Asian Biomedicine
BackgroundThe quadriceps tendon is a promising alternative graft choice for anterior cruciate ligament (ACL) reconstruction. Morphology of the graft directly affects the biomechanical properties. However, a few studies are evaluating the anatomical structures of quadriceps tendon as a graft in Asian population. ObjectiveTo define the anatomical str...
Published in Asian Biomedicine
BackgroundMultidrug-resistant bacteria are becoming more hazardous day by day for human health all over the world, and the scientific community is trying hard to resolve this issue by various approaches. One of the very common approaches is to bind drugs to nanoparticles and study enhanced antibacterial properties. ObjectiveTo compare simultaneousl...
Published in Asian Biomedicine
BackgroundThe arylidene indanone scaffold has contributed many lead molecules in chemotherapeutic anticancer agent research. ObjectivesTo determine the oxidant-scavenging activities and antiproliferative activity of (2E)-2-benzylidene-4,7-dimethyl-2,3-dihydro-1H-inden-1-one (MLT-401), an arylidene indanone derivative. MethodsJurkat cells, primary l...
