Le Goff, Maëlle Cornec, Divi Jousse-Joulin, Sandrine Guellec, Dewi Costa, Sebastian Marhadour, Thierry Le Berre, Rozenn Genestet, Steeve Cochener, Béatrice Boisrame-Gastrin, Sylvie
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Arthritis Research & Therapy
BackgroundThe objective was to evaluate concordance between 2002 American-European Consensus Group (AECG) and 2016 American College of Rheumatology (ACR)/European League Against Rheumatism (EULAR) classification criteria for primary Sjögren’s syndrome (pSS) and to assess how salivary gland ultrasonography (SGUS) might improve the classification of ...
Sobue, Yasumori Kojima, Toshihisa Kurokouchi, Kazutoshi Takahashi, Shigeo Yoshida, Hiroaki Poole, Robin Ishiguro, Naoki
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Arthritis Research & Therapy
BackgroundWe aimed to determine whether synovial fluid (SF) biomarkers can predict the progression of articular cartilage damage as determined by arthroscopic evaluation during and after anterior cruciate ligament (ACL) reconstruction.MethodsArthroscopic assessment of articular cartilage damage was performed twice in 62 patients, first during ACL r...
Hoang, Anh Goodman, Susan M. Navarro-Millán, Iris Y. Mandl, Lisa A. Figgie, Mark P. Bostrom, Mathias P. Padgett, Douglas E. Sculco, Peter K. McLawhorn, Alexander S. Singh, Jasvinder A.
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Published in
Arthritis Research & Therapy
BackgroundOur objective in this study was to examine whether stakeholders further endorse the core domain set proposed by the Outcome Measures in Rheumatology Trials (OMERACT) total joint replacement (TJR) working group.MethodsWe emailed a survey to 3810 hip/knee arthroplasty patients and 49 arthroplasty surgeons at a high-volume arthroplasty cente...
Toral, Marta Jiménez, Rosario Romero, Miguel Robles-Vera, Iñaki Sánchez, Manuel Salaices, Mercedes Sabio, José Mario Duarte, Juan
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Arthritis Research & Therapy
BackgroundWe tested whether GW0742, a peroxisome proliferator-activated receptor beta/delta (PPARβ/δ) agonist, improves endothelial dysfunction induced by plasma from patients with systemic lupus erythematosus (SLE) involving the inhibition of endoplasmic reticulum (ER) stress.MethodsA total of 12 non-pregnant women with lupus and 5 non-pregnant he...
Martin, Myriam Smoląg, Karolina I. Björk, Albin Gullstrand, Birgitta Okrój, Marcin Leffler, Jonatan Jönsen, Andreas Bengtsson, Anders A. Blom, Anna M.
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Arthritis Research & Therapy
BackgroundIn the present study, we sought to evaluate the complement activation product C4d as a marker for lupus nephritis in systemic lupus erythematosus (SLE).MethodsC4d levels were determined by enzyme-linked immunosorbent assay in plasma samples of patients with established SLE using a novel approach based on detection of a short linear cleava...
Benyamine, Audrey Magalon, Jérémy Cointe, Sylvie Lacroix, Romaric Arnaud, Laurent Bardin, Nathalie Rossi, Pascal Francès, Yves Bernard-Guervilly, Fanny Kaplanski, Gilles
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Arthritis Research & Therapy
BackgroundThe disruption of endothelial homeostasis is a major determinant in the pathogenesis of systemic sclerosis (SSc) and is reflected by soluble and cellular markers of activation, injury and repair. We aimed to provide a combined assessment of endothelial markers to delineate specific profiles associated with SSc disease and its severity.Met...
Sato, Hiroshi Muraoka, Sei Kusunoki, Natsuko Masuoka, Shotaro Yamada, Soichi Ogasawara, Hideaki Imai, Toshio Akasaka, Yoshikiyo Tochigi, Naobumi Takahashi, Hiroshi
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Arthritis Research & Therapy
BackgroundAdipokines are bioactive hormones secreted by adipose tissues. Resistin, an adipokine, plays important roles in the regulation of insulin resistance and inflammation. Resistin levels are known to be increased in the serum and synovial fluid of rheumatoid arthritis (RA) patients. However, the pathogenic role of resistin in RA has not yet b...
Cudejko, Tomasz van der Esch, Martin van der Leeden, Marike van den Noort, Josien C. Roorda, Leo D. Lems, Willem Twisk, Jos Steultjens, Martijn Woodburn, James Harlaar, Jaap
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Arthritis Research & Therapy
BackgroundWe aimed to (i) evaluate the immediate effect of a soft knee brace on pain, activity limitations, self-reported knee instability, and self-reported knee confidence, and (ii) to assess the difference in effect between a non-tight and a tight soft brace in patients with knee osteoarthritis (OA).MethodsForty-four patients with knee OA and se...
Lai, Ning-Sheng Yu, Hui-Chun Tung, Chien-Hsueh Huang, Kuang-Yung Huang, Hsien-Bin Lu, Ming-Chi
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Arthritis Research & Therapy
BackgroundTumor necrosis factor-alpha (TNF-α) can cause diverse T cell dysfunctions in patients with rheumatoid arthritis (RA). It is involved in the regulation of microRNAs (miRNAs) expression in different cell types. We hypothesized that the expression of T cell miRNAs would be affected by TNF-α, and these miRNAs could participate in the immunopa...
Larrañaga-Vera, Ane Lamuedra, Ana Pérez-Baos, Sandra Prieto-Potin, Ivan Peña, Leticia Herrero-Beaumont, Gabriel Largo, Raquel
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Arthritis Research & Therapy
BackgroundMetabolic syndrome (MetS) may be associated with knee osteoarthritis (OA), but the association between the individual components and OA are not well-understood. We aimed to study the effect of hypercholesterolemia on synovial inflammation in knee OA.MethodsOA was surgically induced in rabbits fed with standard diet (OA group, n = 10) or i...
