McKeever, S Johnston, L Davidson, A J
Published in
Anaesthesia and intensive care
Processed electroencephalography is used in adults to guide anaesthesia, but the algorithms used may not apply to infants. Knowledge of infants' electroencephalogram (EEG) responses to anaesthetics is fragmentary. An earlier pilot study suggested amplitude-integrated EEG (aEEG) may be a useful measure of anaesthetic effect. The aim of this study wa...
Krishnamurthy, R B Upton, R N Fajumi, A O Lai, S Charlton, C S Ousley, R M Martinez, A M McConnell, H O'Connor, S N Ong, J
...
Published in
Anaesthesia and intensive care
This study aimed to characterise and compare the absorption pharmacokinetics of a single subcutaneous dose of oxycodone in critically ill patients and healthy subjects. Blood samples taken at intervals from two minutes to eight hours after a subcutaneous dose of oxycodone in patients (5 mg) and healthy volunteers (10 mg) were assayed using high per...
Leslie, K Myles, P S Halliwell, R Paech, M J Short, T G Walker, S
Published in
Anaesthesia and intensive care
The POISE Trial was a randomised, placebo-controlled, double-blind study of the effectiveness of perioperative beta-blockade in preventing cardiac events including death in 8351 patients. Our hypothesis was that knowledge of the results of the POISE Trial would either increase or decrease the use of effective perioperative beta-blockade, depending ...
Stephens, L C Bruessel, T
Published in
Anaesthesia and intensive care
We undertook a systematic review to determine the optimal dose of oxytocin after elective caesarean section or caesarean section in labouring women. We identified seven trials. These trials raise questions about the use of high dose (10 international units; IU) or moderate dose (5 IU) oxytocin in both settings and provide evidence that lower doses ...
McLoughlin, P D
Published in
Anaesthesia and intensive care
Ng, M D Manikappa, S
Published in
Anaesthesia and intensive care
A 33-year-old parturient experienced seizures, then an ischaemic stroke after caesarean section, while undergoing an epidural blood patch for dural puncture. A diagnosis of normotensive late postpartum eclampsia, with either a posterior reversible encephalopathy syndrome or postpartum vasculopathy, leading to stroke, was made - based primarily on a...
Smith, N A Martin, D
Published in
Anaesthesia and intensive care
Muller, G Guillon, A Garot, D Mercier, E Perrotin, D
Published in
Anaesthesia and intensive care
Stadler, M Boogaerts, J G
Published in
Anaesthesia and intensive care
Lee, R A van Zundert, T C R V van Koesveld, J J M van Zundert, A A J Stolker, R-J Wieringa, P A Gatt, S P
Published in
Anaesthesia and intensive care
The demand for increased patient safety has led to greater use of simulation training of health professionals performing medical procedures. The study aim was to evaluate the usefulness of the Mediseus® Epidural Simulator in teaching basic epidural needle-handling skills. Three groups of 15 anaesthetists (Novice=zero to two year anaesthesia trainee...
