Published in American journal of epidemiology
Uterine leiomyomata (UL) are associated with severe reproductive morbidity and are the primary indication for hysterectomy in the United States. A recent prospective cohort study of Black women reported positive associations between intakes of marine-sourced ω-3 fatty acids and UL risk. We examined whether intakes of dietary fat were associated wit...
Published in American journal of epidemiology
A semiquantitative risk factor has 2 components: any exposure (yes/no) and the quantitative amount of exposure (if exposed). We describe the statistical properties of alternative analyses with such a risk factor using linear, logistic, or Cox proportional hazards models. Often analyses employ the amount exposed as a single quantitative covariate, i...
Published in American journal of epidemiology
The development of tools for power and sample-size calculations for mediation analysis has lagged far behind the development of methods. The accompanying paper by Rudolph et al. (Am J Epidemiol. 2020;189(12):1559-1567) is a helpful contribution in using simulations as a tool for power calculations for more complex methods and settings. Much work re...
Published in American journal of epidemiology
Mediation analyses are valuable for examining mechanisms underlying an association, investigating possible explanations for nonintuitive results, or identifying interventions that can improve health in the context of nonmanipulable exposures. However, designing a study for the purpose of answering a mediation-related research question remains chall...
Published in American journal of epidemiology
We estimated the association between regular physical activity and the incidence of restrictive spirometry pattern. Forced expiratory volume in 1 second (FEV1), forced vital capacity (FVC), and physical activity were assessed in 2 population-based European cohorts (European Community Respiratory Health Survey: n = 2,757, aged 39-67 years; and Swiss...
Published in American journal of epidemiology
There is broad agreement that religion is a social determinant of health. In the article by Chen and VanderWeele (Am J Epidemiol. 2018;187(11):2355-2364), the authors took an outcome-wide approach to demonstrate associations between religious practices early in the life course (regular service attendance and prayer/mediation) and a wide range of he...
Published in American journal of epidemiology
Published in American journal of epidemiology
Several studies have reported associations between prenatal acetaminophen exposure and behavioral outcomes in young children. We aimed to evaluate the associations of prenatal and postnatal exposures to acetaminophen with behavioral problems in children at age 11 years, using behavioral measures reported by parents and children. We studied 40,934 m...
Published in American journal of epidemiology
Asthma leads to increased weight gain in nonpregnant populations, but studies have not examined this association within the context of pregnancy. This study examines the association between asthma and perinatal weight trajectories in the Breathe - Wellbeing, Environment, Lifestyle, and Lung Function Study (2015-2019). Multilevel linear spline model...
Published in American journal of epidemiology
