Zhang, Yuantao Lei, Yuan Jiang, Hong Li, Xingzhen Feng, Huiling
Published in
American Journal of Translational Research
Objective: To evaluate the hypoxic ischemic encephalopathy (HIE) and multiple organ dysfunction (MOD) in neonates and analyze the correlation between the two disorders. Methods: From January 2018 to January 2020, infants with HIE who were born in our hospital at or above 37 weeks of gestation, and those with ischemic hypoxic encephalopathy at or ab...
Jalasutram, Anvesh Caniglia, John L Velpula, Kiran K Guda, Maheedhara R Bach, Sarah E Tsung, Andrew J
Published in
American Journal of Translational Research
The molecular mechanisms underlying progression from astrocytoma to secondary glioblastoma are poorly understood. Telomerase reverse transcriptase (TERT), a gene encoding for the catalytic subunit of telomerase, is upregulated in various cancers. Upregulation of TERT is a likely mechanism by which malignant cells delay senescence and evade cell dea...
Bai, Ling Yang, Likun Shi, Xiaoyan Huang, Wan
Published in
American Journal of Translational Research
Objectives: To investigate the effect of a new nursing method combining Plan-Do-Check-Act (PDCA) circulation management and nursing on the prognosis of patients with severe pneumonia. Methods: The clinical records of 98 patients treated in the Second Affiliated Hospital of Xi’an Jiaotong University from January 2019 to January 2021 were retrospecti...
Lin, Siran Zhang, Wei Xu, Yuzhen Liu, Qianqian Zhang, Wenhong Shao, Lingyun
Published in
American Journal of Translational Research
Objectives: Chronic otitis media (COM) is a common disease and causes significant hearing impairment in many adults. Our study aimed to investigate the immune response in COM adult patients through RNA sequencing. Methods: In this study, we enrolled four adult COM patients and five healthy controls (HCs) to analyze and compare the mRNA signatures i...
Xie, Xianxin Li, Huan Wang, Cong Li, Weijie Xie, Didi Li, Mo Jiang, Daqing
Published in
American Journal of Translational Research
Breast cancer (BC) is mainly treated by surgery combined with chemotherapy, radiotherapy, and drugs comprehensively in clinical practice, and such a combined treatment can improve the survival rate of patients. This study was designed to determine the effect of modified radical mastectomy (MRM) combined with neo-adjuvant chemotherapy on patients wi...
Yang, Xudong Wang, Yali Liu, Yongping Shang, Lei Cheng, Zhijian Fang, Liping Zhang, Jian Feng, Yifan Zhang, Kuiwei Jiang, Shanjiao
...
Published in
American Journal of Translational Research
Objectives: Traditional Chinese medicine has been reported to be effective in the treatment of epidemic diseases. Here, we aimed to investigate the effects of combined therapy of Chinese and western medicine on coronavirus disease 2019 (COVID-19). Methods: A total of 60 patients diagnosed with COVID-19 were enrolled. Both the ordinary and severely ...
Bao, Jian Wu, Zhengsheng Zhang, Congjun Zhang, Mingjun Wang, Yi Li, Hongxia Sun, Xiang Gao, Junfeng Ge, Lei Li, Yuzhi
...
Published in
American Journal of Translational Research
Objective: To explore the efficacy and mechanism of osimertinib combined with bevacizumab in treating postoperative epidermal growth factor receptor (EGFR) positive stage II-IIIA lung adenocarcinoma. Methods: In this retrospective study, one hundred and thirty patients with postoperative EGFR positive stage II-IIIA lung adenocarcinoma were divided ...
Fang, Jingyun Zhang, Xueli
Published in
American Journal of Translational Research
Objectives: This prospective study aimed to explore the effects of various doses of rosuvastatin on the hemodynamic changes, highly sensitive C-reactive protein (hs-CRP) and interleukin-6 (IL-6) levels in elderly patients with unstable angina pectoris. Methods: One-hundred and six elderly patients with unstable angina pectoris were enrolled and div...
Zhou, Yi-Wen Zhang, Le-Yin Ding, Shu-Ning Zhang, An-Lai Zhu, Ying Chen, Yu-Xuan Zhang, Qi-Chen Sun, Lei-Tao Yu, Jie-Ru
Published in
American Journal of Translational Research
Background: With a high incidence globally, deaths form gastric cancer (GC) are not rare. Early diagnosis is crucial to ameliorate its prognosis. Confocal laser endomicroscopy (CLE) and narrow band imaging (NBI) have been extensively applied in gastroscopy, particularly when it comes to the detection and management of premalignant gastric lesion. O...
Lee, Kyungho Jang, Hye Ryoun Jeon, Junseok Yang, Kyeong Eun Lee, Jung Eun Kwon, Ghee Young Kim, Dae Joong Kim, Yoon-Goo Huh, Wooseong
Published in
American Journal of Translational Research
The repair mechanism after ischemic acute kidney injury (AKI) involves complex immunologic processes, which determine long-term renal outcomes. Through investigating two murine ischemia-reperfusion injury (IRI) models: bilateral IRI (BIRI) and unilateral IRI (UIRI), we aimed to determine an appropriate murine model that could simulate the recovery ...
