Zhang, Fei Reveron, Helen Spies, Benedikt C Van Meerbeek, Bart Chevalier, Jérôme
Published in
Acta biomaterialia
High strength and translucency are generally not coincident in one restorative material and there is still a continuous development for a better balance between these two properties. Zirconia and lithium-disilicate glass-ceramics are currently the most popular alternatives for monolithic restorations. In this work, the mechanical properties and mor...
Masamoto, Kazutaka Fujibayashi, Shunsuke Yabutsuka, Takeshi Hiruta, Tomoko Otsuki, Bungo Okuzu, Yaichiro Goto, Koji Shimizu, Takayoshi Shimizu, Yu Ishizaki, Chihiro
...
Published in
Acta biomaterialia
We recently developed a surface treatment, "precursor of apatite" (PrA), for polyetheretherketone (PrA-PEEK) via a simple, low-temperature process aiming to achieve stronger and faster adhesion to bone. The treatment involves three steps: H2SO4 immersion, exposure to O2 plasma discharge, and alkaline simulated body fluid (alkaline SBF) treatment. T...
Vasconcelos, Daniela P de Torre-Minguela, Carlos Gomez, Ana I Águas, Artur P Barbosa, Mário A Pelegrín, Pablo Barbosa, Judite N
Published in
Acta biomaterialia
Chitosan (Ch) is used in different biomedical applications to promote tissue repair. However, tissue injury caused by biomaterial implantation lead to the release of danger signals that engage different inflammatory pathways on the host. Different implanted materials activate the inflammasome leading to the modulation of the immune response. Here w...
Ruland, Andres Gilmore, Kerry J Daikuara, Luciana Y Fay, Cormac D Yue, Zhilian Wallace, Gordon G
Published in
Acta biomaterialia
In the present work we have revisited the application of quantitative ultrasound imaging (QUI) to cellular hydrogels, by using the reference phantom method (RPM) in combination with a local attenuation compensation algorithm. The investigated biological samples consisted of cell-laden collagen hydrogels with PC12 neural cells. These cell-laden hydr...
Song, Zhaoqiang Ni, Yong Cai, Shengqiang
Published in
Acta biomaterialia
Twisted or oscillated plywood structure can be often found in biological composites such as claws of lobsters, bone of mammals, dactyl club of mantis shrimps, and exoskeleton of beetles, which exhibits a combination of high stiffness, high fracture toughness and low density. However, there lacks a quantitative understanding of the relationship betw...
Lee, Sungjin Ahn, Hyung Jun
Published in
Acta biomaterialia
Adeno-associated virus (AAV) is a promising vector for systemic delivery of siRNA because of its long-term expression ability without immunogenicity and pathogenicity. However, its broad host tropism and lack of tissue specificity have limited clinical applications such as cancer therapy. Therefore, redirecting the natural tropism of AAV vectors to...
Schetters, Sjoerd T T Jong, Wouter S P Horrevorts, Sophie K Kruijssen, Laura J W Engels, Steef Stolk, Dorian Daleke-Schermerhorn, Maria H Garcia-Vallejo, Juan Houben, Diane Unger, Wendy W J
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Published in
Acta biomaterialia
Outer membrane vesicles (OMVs) are vesicular nano-particles produced by Gram-negative bacteria that are recently being explored as vaccine vector. The fact that OMVs can be efficiently produced by a hypervesiculating Salmonella typhimurium strain, are packed with naturally-occurring adjuvants like lipopolysaccharides (LPS), and can be engineered to...
Barnes, Megan Feit, Corbin Grant, Trudy-Ann Brisbois, Elizabeth J
Published in
Acta biomaterialia
Hospital associated infections (HAIs), infections acquired by patients during care in a hospital, remain a prevalent issue in the healthcare field. These infections often occur with the use of indwelling medical devices, such as endotracheal tubes (ETTs), that can result in ventilator-associated pneumonia (VAP). When examining the various routes of...
Costa, Ana de Souza Carvalho-Wodarz, Cristiane Seabra, Vítor Sarmento, Bruno Lehr, Claus-Michael
Published in
Acta biomaterialia
Predictive in vitro models are valuable alternatives to animal experiments for evaluating the transport of molecules and (nano)particles across biological barriers. In this work, an improved triple co-culture of air-blood barrier was set-up, being exclusively constituted by human cell lines that allowed to perform experiments at air-liquid interfac...
Konishi, Toshiisa Nagano, Yasuyuki Maegawa, Marina Lim, Poon Nian Thian, Eng San
Published in
Acta biomaterialia
Substitution of inorganic ions into β-tricalcium phosphate (β-TCP) is a well-known approach for facilitating biological functions of bioceramics. However, the dissolution mechanism of those β-TCPs is still under intensive debates. In the present study, the effect of copper substitution into β-TCP crystal structure on the local chemical structure an...
