Bozzetto, L. De Natale, C. Di Capua, L. Della Corte, G. Patti, L. Maione, S. Riccardi, G. Rivellese, A. A. Annuzzi, G.
Published in
Acta Diabetologica
The aim of the study was to evaluate whether two dietary approaches recommended for diabetes mellitus and cardiovascular prevention—high-MUFA or complex carbohydrates/fiber—differently influence inflammation. A 4-week crossover study in 12 individuals with type 2 diabetes was performed. Fasting and postprandial hs-CRP plasma levels were not signifi...
Buscemi, Silvio Canino, Baldassare Batsis, John A. Buscemi, Chiara Calandrino, Vincenzo Mattina, Alessandro Arnone, Mariangela Caimi, Gregorio Cerasola, Giovanni Verga, Salvatore
...
Published in
Acta Diabetologica
Aerobic capacity, as indicated by maximal oxygen uptake (VO2 max) has an important role in contrasting the traditional cardiovascular risk factors and preventing cardiovascular morbidity and mortality. It is known that endothelial function, measured as flow-mediated dilation (FMD) of the brachial artery, is strictly linked to atherogenesis and card...
López-Tinoco, Cristina Roca, Mar García-Valero, Amor Murri, Mora Tinahones, Francisco J. Segundo, Carmen Bartha, José L. Aguilar-Diosdado, Manuel
Published in
Acta Diabetologica
The relationship between late-onset gestational diabetes mellitus [GDM] and oxidative stress is not well known, and the importance of the oxidant/antioxidant equilibrium in the clinical evolution and its complications require elucidation. The aim of the study was to evaluate the relationships between maternal levels of markers of oxidative stress i...
Bozorgmanesh, Mohammadreza Hadaegh, Farzad Azizi, Fereidoun
Published in
Acta Diabetologica
We validated the transportability of the updated diabetes prediction model from Atherosclerosis Risk in Communities (ARIC) Study, to a Middle Eastern population. We investigated 3,721 participants of the Tehran Lipid and Glucose Study (TLGS) aged ≥20 years, free of diabetes at baseline. They underwent a standard 75gr 2-h post-challenge plasma gluco...
Brun, Jean-Frédéric Ghanassia, Edouard Fédou, Christine Bordenave, Sylvain Raynaud de Mauverger, Eric Mercier, Jacques
Published in
Acta Diabetologica
We investigated the measurement of insulin sensitivity (SI) with a standardized hyperglucidic breakfast (SHB) compared to minimal model analysis of an intravenous glucose tolerance test (SI-IVGTT) in 17 patients clinically referred as type 2 diabetics, not yet treated by insulin, and representing a wide range of body mass index and SI. To classify ...
Furuya, M. Hayashino, Y. Tsujii, S. Ishii, H. Fukuhara, S.
Published in
Acta Diabetologica
A simple tool consisting of two questions for screening depressive symptoms has been shown to be useful in primary care settings, but its validity in patients with diabetes has yet to be evaluated. We compared the test performance of this two-question instrument with that of WHO (The World Health Organization)-5. We consecutively enrolled 153 patie...
Kouidhi, Soumaya Berrhouma, Rym Rouissi, Kamel Jarboui, Slim Clerget-Froidevaux, Marie-Stéphanie Seugnet, Isabelle Bchir, Fattouma Demeneix, Barbara Guissouma, Hajer Elgaaied, Amel Benammar
...
Published in
Acta Diabetologica
Cellular resistance to insulin caused by reduced glucose transport and metabolism is a primary defect leading to the development of metabolic disease. While the etiology of insulin resistance is multifactorial, reduced insulin action is associated with impaired activity of the glucose transporter GLUT4 in insulin-sensitive tissues. Yet, the role of...
Cubas-Dueñas, Ileana Cabrera-Rode, Eduardo Sarmiento, Luis Molina, Gisela Fonseca, Magilé Arranz, Celeste Domínguez, Emma González, Pedro Vera, Manuel Díaz-Horta, Oscar
...
Published in
Acta Diabetologica
Type 1 diabetes (T1D) results from the interaction of genetic and environmental factors. Previous studies indicate an association between detection of Enterovirus (EV) genome in blood and the clinical onset of T1D. Insulin resistance can also represent a risk factor for progression to clinically overt T1D. This study aimed at evaluating whether the...
Wang, An-ping Li, Xia Zheng, Ying Liu, Bi-lian Huang, Gan Yan, Xiang Liu, Zhenqi Zhou, Zhiguang
Published in
Acta Diabetologica
Since most of the current studies of thiazolidinediones (TZDs) are only focused on improving glycemic control, increasing insulin sensitivity, and regulating inflammatory states in Type 2 Diabetes, it is still controversial whether TZDs have direct, protective effects on pancreatic β-cells in autoimmune diabetes. Here, we show the protective effect...
Kim, Tae Ho Choi, Sung E Ha, Eun Suk Jung, Jong Gab Han, Seung Jin Kim, Hae Jin Kim, Dae Jung Kang, Yup Lee, Kwan Woo
Published in
Acta Diabetologica
We investigated the cytokines and mechanisms involved in the induction of insulin resistance in human skeletal muscle. Ten subjects with impaired glucose tolerance (IGT) and 10 control subjects were recruited. We performed biopsies on the vastus lateralis muscle and used immunoblotting to determine levels of inflammatory cytokines, Toll-like recept...
