Zhao, Zhijuan Cui, Xiaodong Ma, Xiaoli Wang, Zhuanhua
Published in
Acta Biochimica et Biophysica Sinica
The self-nanoemulsifying drug delivery system has shown many advantages in drug delivery. In this study, a self-nanoemulsifying drug delivery system of buckwheat flavonoids was prepared for enhancing its antioxidant activity and oral bioavailability. A nanoemulsion of buckwheat flavonoids was developed and characterized, and its antioxidant, in vit...
Bosevski, Marijan Krstevski, Gorjan Bosevska, Golubinka Kapsarov, Kosta Dodic, Emilija Feehan, Jack Stojanoska, Lily Apostolopoulos, Vasso
Published in
Acta Biochimica et Biophysica Sinica
Zhang, Li Li, Dandan Zhang, Juan Yan, Ping Liu, Xueqin Wang, Lei Khan, Ajab Liu, Zhizhen Mu, Jianbing Xu, Jun
...
Published in
Acta biochimica et biophysica Sinica
The central nervous system (CNS) diseases are still a major cause of morbidity and mortality throughout the world, which imposes heavy burden on the development of society. Ethionine is a non-proteinogenic amino acid having similar chemical structure and activity to that of methionine, with which it competes. Previous studies have confirmed that et...
Shi, Rongfeng Lian, Weishuai Jin, Yinpeng Cao, Chuanwu Han, Shilong Yang, Xiaohu Zhao, Suming Li, Maoquan Zhao, Hui
Published in
Acta Biochimica et Biophysica Sinica
Diabetic foot ulcer (DFU) is one of diabetic complications, which is frequently present and tormented in diabetes mellitus. Most multipotent mesenchymal stromal cells (MSCs) are capable of immune evasion, providing an allogeneic, ready-to-use, cell product option for therapeutic applications. The beneficial effect of MSCs for the treatment of a var...
Xu, Guangmeng Sun, Yajuan He, Huaiqiang Xue, Qiuli Liu, Yajie Dong, Lihua
Published in
Acta Biochimica et Biophysica Sinica
In this study, we aimed to explore the effect of TrkB-PLC/IP3 pathway on intestinal inflammatory factors and enterocyte apoptosis in mice with colitis. The mouse model of ulcerative colitis was established by medication, and 40 SPF C57BL/6J mice (8 weeks old) were randomly divided into normal group (healthy mice, n = 10), control group (sham-operat...
Zhang, Yiwen Zhang, Xiaoxia Xing, Zumin Tang, Shuyi Chen, Hanwen Zhang, Zhongqi Li, Jiyuan Li, Yalan
Published in
Acta Biochimica et Biophysica Sinica
Bone cancer pain (BCP) is a common chronic pain that is caused by a primary or metastatic bone tumor. More detailed molecular mechanisms of BCP are warranted. In this study, we established a BCP rat model. The von Frey hair test, body weight, and hematoxylin and eosin staining were employed. We screened differentially expressed circRNAs (DECs) betw...
Yang, Xin Arslan, Mehboob Liu, Xingjian Song, Haozhi Du, Mengtan Li, Yinü Zhang, Zhifang
Published in
Acta Biochimica et Biophysica Sinica
Newcastle disease virus (NDV) causes severe economic losses through severe morbidity and mortality and poses a significant threat to the global poultry industry. Significant efforts have been made to develop novel vaccines and therapeutics; however, the interaction of NDV with the host is not yet fully understood. Interferons (IFNs), an integral co...
Saremi, Kamelia Rad, Sima Kianpour Khalilzadeh, Maryam Hussaini, Jamal Majid, Nazia Abdul
Published in
Acta Biochimica et Biophysica Sinica
Chlorine is shown to possess anti-gastric ulcer activity, since it can inactivate Helicobacter pylori , which is regarded as one of the most common risk factors for causing gastric problems. In the current study, the gastroprotective property of a novel dichloro-substituted Schiff base complex, 2, 2′- [−1, 2-cyclohexanediylbis(nitriloethylidyne)] b...
Zhang, Juan Yang, Lihong Yu, Juan Yang, Qiaoyan Mu, Jianbing Xie, Jun
Published in
Acta biochimica et biophysica Sinica
Hao, Pan Cui, Xia Liu, Jing Li, Muzi Fu, Yong Liu, Qun
Published in
Acta biochimica et biophysica Sinica
Few information of the function of stearoyl-coenzyme A (CoA) desaturase (SCD) in apicomplaxan parasite has been obtained. In this study, we retrieved a putative fatty acyl-CoA desaturase (TGGT1_238950) by a protein alignment with Plasmodium falciparum SCD in ToxoDB. A typical Δ9-desaturase domain was revealed in this protein. The putative desaturas...
