Affordable Access

Access to the full text

Zirconia-based catalyst for the one-pot synthesis of coumarin through Pechmann reaction

Authors
  • Khan, Shahid Ali1, 2
  • Khan, Sher Bahadar1, 2
  • Asiri, Abdullah M.1, 2
  • Ahmad, Ikram1, 2
  • 1 King Abdulaziz University, Chemistry Department, Faculty of Science, Jeddah, 21589, Saudi Arabia , Jeddah (Saudi Arabia)
  • 2 King Abdulaziz University, Center of Excellence for Advanced Materials Research (CEAMR), Jeddah, Saudi Arabia , Jeddah (Saudi Arabia)
Type
Published Article
Journal
Nanoscale Research Letters
Publisher
Springer (Biomed Central Ltd.)
Publication Date
Jul 26, 2016
Volume
11
Issue
1
Identifiers
DOI: 10.1186/s11671-016-1525-3
Source
Springer Nature
Keywords
License
Green

Abstract

Coumarins play an important role in drug development with diverse biological applications. Herein, we present the synthesis of coumarin through Pechmann reaction by using zirconia-based heterogeneous catalysts (ZrO2-TiO2, ZrO2-ZnO, and ZrO2/cellulose) in a solvent-free condition at room temperature. ZrO2-TiO2, ZrO2-ZnO, and ZrO2/cellulose were identified through spectroscopic techniques such as FESEM, X-ray, EDS, XPS, and FT-IR. ZrO2-TiO2 showed the best catalytic performance while ZrO2/cellulose was inactive. The kinetic parameters were observed in a solvent-free condition as well as in toluene and ethanol. The temperature effect was extensively studied which revealed that increasing the temperature will increase the rate of reaction. The rate of reaction in a solvent-free condition, ethanol, and toluene were 1.7 × 10−3, 1.7 × 10−2, and 5.6 × 10−3 g mol−1 min−1, respectively.

Report this publication

Statistics

Seen <100 times