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The zebrafish heart regenerates after cryoinjury-induced myocardial infarction.

Authors
Type
Published Article
Journal
BMC Developmental Biology
1471-213X
Publisher
Springer (Biomed Central Ltd.)
Publication Date
Volume
11
Pages
21–21
Identifiers
DOI: 10.1186/1471-213X-11-21
PMID: 21473762
Source
Medline
License
Unknown

Abstract

We developed a new cryoinjury model to induce myocardial infarction in zebrafish. Although the initial stages following cryoinjury resemble typical healing in mammals, the zebrafish heart is capable of structural and functional regeneration. Understanding the key healing processes after myocardial infarction in zebrafish may result in identification of the barriers to efficient cardiac regeneration in mammals.

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