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The Zebrafish Dorsolateral Habenula Is Required for Updating Learned Behaviors

Authors
  • Palumbo, Fabrizio1
  • Serneels, Bram1, 2
  • Pelgrims, Robbrecht1
  • Yaksi, Emre1
  • 1 Kavli Institute for Systems Neuroscience and Centre for Neural Computation, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, 7030 Trondheim, Norway
  • 2 KU Leuven, 3000 Leuven, Belgium
Type
Published Article
Journal
Cell Reports
Publisher
Elsevier
Publication Date
Aug 25, 2020
Volume
32
Issue
8
Identifiers
DOI: 10.1016/j.celrep.2020.108054
PMID: 32846116
PMCID: PMC7479510
Source
PubMed Central
Keywords
License
Unknown

Abstract

Palumbo et al. show that juvenile zebrafish can perform conditioned place avoidance (CPA) learning with improved performance across development and repeated training sessions. The authors demonstrate a role for dorsolateral habenula in providing behavioral flexibility, allowing animals to adapt to changing rules during reversal learning.

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