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XRCC1 downregulated through promoter hypermethylation is involved in human gastric carcinogenesis.

Authors
  • Wang, Ping
  • Tang, Jie Ting
  • Peng, Yan Shen
  • Chen, Xiao Yu
  • Zhang, Yan Jie
  • Fang, Jing Yuan
Type
Published Article
Journal
Journal of digestive diseases
Publication Date
Dec 01, 2010
Volume
11
Issue
6
Pages
343–351
Identifiers
DOI: 10.1111/j.1751-2980.2010.00459.x
PMID: 21091896
Source
Medline
License
Unknown

Abstract

The expression of XRCC1 is downregulated in gastric carcinogenesis, and promoter hypermethylation may be one of the mechanisms contributing to its downregulation.

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