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XRCC1 codon 399Gln polymorphism is associated with radiotherapy-induced acute dermatitis and mucositis in nasopharyngeal carcinoma patients.

Authors
  • Li, Haijun
  • You, Yanjie
  • Lin, Canfeng
  • Zheng, Mingzhang
  • Hong, Chaoqun
  • Chen, Jiongyu
  • Li, Derui
  • Au, William W
  • Chen, Zhijian
Type
Published Article
Journal
Radiation Oncology
Publisher
Springer (Biomed Central Ltd.)
Publication Date
Jan 01, 2013
Volume
8
Pages
31–31
Identifiers
DOI: 10.1186/1748-717X-8-31
PMID: 23375119
Source
Medline
License
Unknown

Abstract

Our investigation shows, for the first time, that patients with the XRCC1 399Arg/Gln genotype were more likely to experience severe acute dermatitis and oral mucositis. With further validation, the information can be used to determine personalized radiotherapy strategy.

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