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Wortmannin inhibits proliferation and induces apoptosis of MCF-7 breast cancer cells.

Authors
  • Yun, J
  • Lv, Y G
  • Yao, Q
  • Wang, L
  • Li, Y P
  • Yi, J
Type
Published Article
Journal
European journal of gynaecological oncology
Publication Date
Jan 01, 2012
Volume
33
Issue
4
Pages
367–369
Identifiers
PMID: 23091892
Source
Medline
License
Unknown

Abstract

Wortmannin inhibits proliferation and induces apoptosis of MCF-7 cells in a dose and time-dependent manner, likely through down-regulation of PI3K/Akt signaling and NF-kappaB protein expression.

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