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WNTs in synapse formation and neuronal circuitry.

Authors
  • Park, Mikyoung
  • Shen, Kang
Type
Published Article
Journal
The EMBO Journal
Publisher
EMBO
Publication Date
Jun 13, 2012
Volume
31
Issue
12
Pages
2697–2704
Identifiers
DOI: 10.1038/emboj.2012.145
PMID: 22617419
Source
Medline
License
Unknown

Abstract

Wnt proteins play important roles in wiring neural circuits. Wnts regulate many aspects of neural circuit generation through their receptors and distinct signalling pathways. In this review, we discuss recent findings on the functions of Wnts in various aspects of neural circuit formation, including neuronal polarity, axon guidance, synapse formation, and synaptic plasticity in vertebrate and invertebrate nervous systems.

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