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Wide geographic spread of diverse acquired AmpC beta-lactamases among Escherichia coli and Klebsiella spp. in the UK and Ireland.

Authors
  • Woodford, Neil1
  • Reddy, Suganya
  • Fagan, Elizabeth J
  • Hill, Robert L R
  • Hopkins, Katie L
  • Kaufmann, Mary E
  • Kistler, James
  • Palepou, Marie-France I
  • Pike, Rachel
  • Ward, M Elaina
  • Cheesbrough, John
  • Livermore, David M
  • 1 Centre for Infections, Health Protection Agency, London, NW9 5EQ, UK. [email protected]
Type
Published Article
Journal
The Journal of antimicrobial chemotherapy
Publication Date
Jan 01, 2007
Volume
59
Issue
1
Pages
102–105
Identifiers
PMID: 17110393
Source
Medline
License
Unknown

Abstract

Diverse acquired AmpC enzymes occur in E. coli and Klebsiella spp. isolates in the UK and Ireland, with CIT types the most common. Producers are geographically scattered, but with some local outbreaks. Acquisition of a CMY-2-like enzyme by E. coli epidemic strain A suggests that these enzymes may be poised to become an important public health issue.

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