Whole-Exome Sequencing to Identify Novel Biological Pathways Associated With Infertility After Pelvic Inflammatory Disease.
From the *Department of Epidemiology and Biostatistics, Texas A&M University, College Station, TX; †Department of Pediatrics, ‡Department of Biostatistics, University of North Carolina Chapel Hill, Chapel Hill, NC; §Institute for Genome Sciences and Society, Texas A&M University, College Station, TX; ¶University of Texas School of Public Health, Houston, TX; and ∥Department of Epidemiology, University of Pittsburgh, Pittsburgh, PA.
- Published Article
Sexually transmitted diseases
- Publication Date
Jan 01, 2017
Focus genes were enriched in pathways that impact innate and adaptive immunity, protein kinase A activity, cellular growth, and DNA repair. These may alter host resistance or immunopathology after infection. Targeted sequencing of biological pathways identified in this study may provide insight into STI-related infertility.
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This record was last updated on 06/09/2018 and may not reflect the most current and accurate biomedical/scientific data available from NLM.
The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/27898568