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Whole-body SPECT/CT for bone scintigraphy: diagnostic value and effect on patient management in oncological patients.

Authors
  • Palmedo, H
  • Marx, C
  • Ebert, A
  • Kreft, B
  • Ko, Y
  • Türler, A
  • Vorreuther, R
  • Göhring, U
  • Schild, H H
  • Gerhardt, T
  • Pöge, U
  • Ezziddin, S
  • Biersack, H-J
  • Ahmadzadehfar, H
Type
Published Article
Journal
European Journal of Nuclear Medicine
Publisher
Springer-Verlag
Publication Date
Jan 01, 2014
Volume
41
Issue
1
Pages
59–67
Identifiers
DOI: 10.1007/s00259-013-2532-6
PMID: 23974666
Source
Medline
License
Unknown

Abstract

SPECT/CT significantly improved the specificity and positive predictive value of bone scintigraphy in cancer patients. In breast cancer patients, we found a slight increase in sensitivity. SPECT/CT had a significant effect on clinical management because of correct downstaging and upstaging, better definition of the extent of metastases, and a reduction in further diagnostic procedures.

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