What tuberculosis can teach us about combating multidrug-resistant Gram negative bacilli.
Division of Pediatric Infectious Diseases, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, United States.
Section of Infectious Diseases, Department of Pediatrics, Baylor College of Medicine, Houston, TX, United States.
- Published Article
Journal of clinical tuberculosis and other mycobacterial diseases
- Publication Date
May 01, 2016
There are striking similarities between the dual pandemics of multidrug-resistant tuberculosis (MDR TB) and multidrug-resistant Gram negative bacilli (MDR GNB) despite fundamental differences in the pathogenesis and epidemiology of these pathogens. In this perspective, we highlight several strategies that have been used by the global TB community to address the MDR TB problem, including approaches to: encourage appropriate use of anti-TB medications, enhance appropriate utilization of molecular diagnostic testing, facilitate development of new antimicrobial agents, and strengthen surveillance systems and infection control practices. Understanding the successes and challenges of these strategies for MDR TB control will be instructive for efforts to curb emergence and spread of MDR GNB. © 2016 The Authors.
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The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/31723682