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What to expect of a good vaccine and how to achieve it.

Authors
  • Ada, G L
Type
Published Article
Journal
Vaccine
Publisher
Elsevier
Publication Date
Apr 01, 1988
Volume
6
Issue
2
Pages
77–79
Identifiers
PMID: 3291458
Source
Medline
License
Unknown

Abstract

Vaccines have been used almost exclusively to prevent or control infectious diseases with the aim of long-lasting immunity. Some, composed of attenuated viruses, have been highly successful and this may be due to the generation of high levels of B memory cells and their steady recruitment to form antibody secreting cells. Some diseases, notably AIDS, are a much greater challenge and it will need all the expertise of molecular biologists and immunologists to devise a vaccine which may control the disease. Vaccination to enhance or decrease the action of hormones is now being actively explored as a practical way of controlling fertility in mammals or enhancing selected properties of other hormones. In this situation, the desired effect is for a defined period, possibly one year or less. These requirements underline further the need for controlled release formulations for vaccine delivery.

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