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Well-differentiated inflammatory liposarcoma with metastasis in a 6-y-old cat.

Authors
  • Alvarez, Elizabeth1, 2
  • Dreyfus, Jennifer1, 2
  • Carlson, Tim1, 2
  • Pinkerton, Marie E1, 2
  • Shaffer, Kimberly1, 2
  • 1 Departments of Veterinary Clinical Sciences, School of Veterinary Medicine, University of Wisconsin, Madison, WI (Alvarez, Shaffer).
  • 2 Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin, Madison, WI (Dreyfus, Carlson, Pinkerton).
Type
Published Article
Journal
Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc
Publication Date
Nov 01, 2017
Volume
29
Issue
6
Pages
896–899
Identifiers
DOI: 10.1177/1040638717725349
PMID: 28782430
Source
Medline
Keywords
License
Unknown

Abstract

Liposarcomas are rare malignant tumors showing adipocytic differentiation. We report a well-differentiated liposarcoma in a 6-y-old, male neutered cat with a prominent inflammatory component and metastatic spread to the lungs. The patient was initially presented because of fever, lethargy, and a firm subcutaneous inguinal mass. A Tru-cut biopsy of the mass revealed a mixture of well-differentiated adipocytes and lymphoplasmacytic-histiocytic inflammation, interpreted as panniculitis. The mass was surgically excised but recurred 4 mo later. A second excisional biopsy yielded similar histologic findings. A third recurrence of the mass was associated with lung nodules. Histopathology of the recurring and metastatic masses confirmed the diagnosis of well-differentiated inflammatory liposarcoma with pulmonary metastases. The neoplasm had an intense inflammatory component, which obscured the underlying features of liposarcoma and made differentiation from steatitis difficult. This inflammatory variant of a well-differentiated liposarcoma should be considered as a differential in tumorous steatitis-like lesions.

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