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Weekend vs. weekday admission and clinical outcomes in heart failure patients with and without atrial fibrillation in Taiwan.

Authors
  • Hu, Wei-Syun1, 2, 3
  • Lin, Cheng-Li4
  • 1 School of Medicine, College of Medicine, China Medical University, Taichung, Taiwan. , (China)
  • 2 Division of Cardiovascular Medicine, Department of Medicine, China Medical University Hospital, 2, Yuh-Der Road, Taichung 40447, Taiwan. , (China)
  • 3 Cardiovascular Institute, An-Nan Hospital, China Medical University, Tainan, Taiwan. , (China)
  • 4 Management Office for Health Data, China Medical University Hospital, Taichung 40447, Taiwan. , (China)
Type
Published Article
Journal
European heart journal. Cardiovascular pharmacotherapy
Publication Date
Jun 08, 2022
Volume
8
Issue
4
Pages
346–352
Identifiers
DOI: 10.1093/ehjcvp/pvab047
PMID: 34180528
Source
Medline
Keywords
Language
English
License
Unknown

Abstract

We conducted this study to explore the associations of weekend and weekday admission with the clinical events among heart failure (HF) patients with and without comorbid atrial fibrillation (AF). In this study, we recruited 57 919 HF patients without AF hospitalized on weekends and 57 919 HF patients without AF hospitalized on weekdays. There were 21407 and 21407 HF patients with AF hospitalized on weekends and weekdays, respectively. The outcomes of interest included all-cause mortality, cardiovascular (CV) death, and HF recurrence requiring admission. The Cox proportional hazard regression model was applied to estimate the hazard ratio. Variables found to be statistically significant in a univariable Cox proportional hazard regression model were further examined in a multivariable Cox proportional hazard regression model. The cumulative incidence curves were obtained by the Kaplan-Meier method and assessed by the log-rank test. HF patients with AF and hospitalized on weekends had the highest incidence rates of rehospitalization due to HF (233.8 per 1000 person-years) and CV death (23.9 per 1000 person-years) among four groups. The Kaplan-Meier method shows that HF patients with AF had the higher cumulative incidence of rehospitalization due to HF than the patients without AF. HF patients with AF and hospitalized on weekends are at highest risk of HF recurrence requiring hospitalization among these four groups. © The Author(s) 2021. Published by Oxford University Press on behalf of the European Society of Cardiology.

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