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[Webbing of the neck and nasal bone--prenatal screening for Down syndrome].

Authors
  • Svennekjaer, Sidsel
  • Skibsted, Lillian
Type
Published Article
Journal
Ugeskrift for laeger
Publication Date
Apr 21, 2003
Volume
165
Issue
17
Pages
1768–1771
Identifiers
PMID: 12768905
Source
Medline
License
Unknown

Abstract

The risk of giving birth to a child with Down syndrome increases with maternal age. If in Denmark the mother is older than 35-years she belongs to a high-risk group and will be offered amniocentesis or chorionic villus sampling. We describe different scenarios of risk calculation for Down syndrome based on combinations of nuchal translucency, nasal bone, and/or integrated hormone test. The combination of nuchal translucency and visualisation of the nasal bone between gestational age 11 weeks and 13 + 6 has turned out to be as good a predictive marker as nuchal translucency and integrated hormone test.

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