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A Weak Spot in Multiple Protozoan Parasites.

Authors
  • Wong, Wilson1
  • 1 Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia; Department of Medical Biology, University of Melbourne, Parkville, VIC 3010, Australia. Electronic address: [email protected] , (Australia)
Type
Published Article
Journal
Structure
Publisher
Elsevier
Publication Date
Nov 07, 2017
Volume
25
Issue
11
Pages
1641–1643
Identifiers
DOI: 10.1016/j.str.2017.10.003
PMID: 29117540
Source
Medline
License
Unknown

Abstract

Eukaryotic protozoan parasites, including the etiological agents of malaria, toxoplasmosis, and leishmaniasis, collectively cause significant mortality in humans. In a recent issue of Structure,Jain et al. (2017) identify a set of quinazolinone-based derivatives targeting the parasitic prolyl-tRNA synthetase enzyme as promising drugs for the clearance of diverse parasites.

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine. This record was last updated on 06/09/2018 and may not reflect the most current and accurate biomedical/scientific data available from NLM. The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/29117540
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