Affordable Access

deepdyve-link
Publisher Website

Waist circumference and mortality.

Authors
  • Koster, Annemarie
  • Leitzmann, Michael F
  • Schatzkin, Arthur
  • Mouw, Traci
  • Adams, Kenneth F
  • van Eijk, Jacques Th M
  • Hollenbeck, Albert R
  • Harris, Tamara B
Type
Published Article
Journal
American Journal of Epidemiology
Publisher
Oxford University Press
Publication Date
Jun 15, 2008
Volume
167
Issue
12
Pages
1465–1475
Identifiers
DOI: 10.1093/aje/kwn079
PMID: 18417494
Source
Medline
License
Unknown

Abstract

The authors examined the association between waist circumference and mortality among 154,776 men and 90,757 women aged 51-72 years at baseline (1996-1997) in the NIH-AARP Diet and Health Study. Additionally, the combined effects of waist circumference and body mass index (BMI; weight (kg)/height (m)(2)) were examined. All-cause mortality was assessed over 9 years of follow-up (1996-2005). After adjustment for BMI and other covariates, a large waist circumference (fifth quintile vs. second) was associated with an approximately 25% increased mortality risk (men: hazard ratio (HR) = 1.22, 95% confidence interval (CI): 1.15, 1.29; women: HR = 1.28, 95% CI: 1.16, 1.41). The waist circumference-mortality association was found in persons with and without prevalent disease, in smokers and nonsmokers, and across different racial/ethnic groups (non-Hispanic Whites, non-Hispanic Blacks, Hispanics, and Asians). Compared with subjects with a combination of normal BMI (18.5-<25) and normal waist circumference, those in the normal-BMI group with a large waist circumference (men: > or =102 cm; women: > or =88 cm) had an approximately 20% higher mortality risk (men: HR = 1.23, 95% CI: 1.08, 1.39; women: HR = 1.22, 95% CI: 1.09, 1.36). The finding that persons with a normal BMI but a large waist circumference had a higher mortality risk in this study suggests that increased waist circumference should be considered a risk factor for mortality, in addition to BMI.

Report this publication

Statistics

Seen <100 times